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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1o5iNAD3-oxoacyl-(Acyl carrier protein) reductase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1o5iNAD3-oxoacyl-(Acyl carrier protein) reductase/1.000
2w2lNADD-mandelate dehydrogenase/0.475
4wxlBB2Peptide deformylase/0.467
1yluFMNOxygen-insensitive NAD(P)H nitroreductase/0.458
2hayFMNPutative NAD(P)H-flavin oxidoreductase/0.456
4cqnILALeucine--tRNA ligase/0.456
2cbsR13Cellular retinoic acid-binding protein 2/0.454
1sesAHXSerine--tRNA ligase6.1.1.110.451
2wd4TBVAscorbate peroxidase/0.450
1lrjUD1UDP-glucose 4-epimerase5.1.3.20.449
4oi2ADPProtein clpf-1/0.449
4d03NAPPhenylacetone monooxygenase1.14.13.920.447
4n9iPCGCatabolite expression activator/0.447
5iw5NMNNADH pyrophosphatase/0.446
2ylrNAPPhenylacetone monooxygenase1.14.13.920.445
2qr1ADP5'-AMP-activated protein kinase subunit gamma/0.444
3dl0AP5Adenylate kinase/0.444
3zc3NAPFerredoxin--NADP reductase1.18.1.20.444
3wecAUICytochrome P450/0.443
1i3mUD1UDP-glucose 4-epimerase/0.442
4d04NAPPhenylacetone monooxygenase1.14.13.920.442
1i3lGDUUDP-glucose 4-epimerase/0.441
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.441
4wriOKAOkadaic acid binding protein 2-alpha/0.441
3cisATPUniversal stress protein Rv2623/0.440
4c77N01Phenylacetone monooxygenase1.14.13.920.440