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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1lpfFADDihydrolipoyl dehydrogenase1.8.1.4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1lpfFADDihydrolipoyl dehydrogenase1.8.1.41.000
3ladFADDihydrolipoyl dehydrogenase/0.607
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.557
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.554
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.550
3urhFADDihydrolipoyl dehydrogenase/0.541
1zx9FADMercuric reductase1.16.1.10.537
2yquFADDihydrolipoyl dehydrogenase/0.532
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.530
2eq9FADDihydrolipoyl dehydrogenase/0.525
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.522
4jq9FADDihydrolipoyl dehydrogenase/0.522
1zk7FADMercuric reductase1.16.1.10.521
2r9zFADGlutathione amide reductase/0.517
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.514
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.509
2eq8FADDihydrolipoyl dehydrogenase/0.494
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.486
3ic9FADPutative dihydrolipoamide dehydrogenase/0.484
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.483
1k4qFADGlutathione reductase, mitochondrial1.8.1.70.465
1lvlFADDihydrolipoyl dehydrogenase1.8.1.40.463
2gh5FADGlutathione reductase, mitochondrial1.8.1.70.463
1f8wFADNADH peroxidase1.11.1.10.462
2nvkFADThioredoxin reductase 1, mitochondrial1.8.1.90.460
1bwcFADGlutathione reductase, mitochondrial1.8.1.70.459
2a8xFADDihydrolipoyl dehydrogenase1.8.1.40.459
1xdiFADNAD(P)H dehydrogenase (quinone)/0.458
1h6vFADThioredoxin reductase 1, cytoplasmic1.8.1.90.456
1gerFADGlutathione reductase1.8.1.70.454
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.453
3dk9FADGlutathione reductase, mitochondrial1.8.1.70.453
3cgbFADCoenzyme A disulfide reductase/0.451
2cfyFADThioredoxin reductase 1, cytoplasmic1.8.1.90.449
3grsFADGlutathione reductase, mitochondrial1.8.1.70.448
3sqpFADGlutathione reductase, mitochondrial1.8.1.70.448
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.447
1zmdFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.445
1geuFADGlutathione reductase1.8.1.70.442
2eq7FADDihydrolipoyl dehydrogenase/0.441