sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1kt3 | RTL | Retinol-binding protein 4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1kt3 | RTL | Retinol-binding protein 4 | / | 1.000 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.645 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.633 | |
| 1kt4 | RTL | Retinol-binding protein 4 | / | 0.599 | |
| 1aqb | RTL | Retinol-binding protein 4 | / | 0.587 | |
| 1iiu | RTL | Retinol-binding protein 4 | / | 0.576 | |
| 1brp | RTL | Retinol-binding protein 4 | / | 0.568 | |
| 1fel | FEN | Retinol-binding protein 4 | / | 0.490 | |
| 3fmz | 2T1 | Retinol-binding protein 4 | / | 0.483 | |
| 1kt5 | RTL | Retinol-binding protein 4 | / | 0.475 | |
| 1osv | CHC | Bile acid receptor | / | 0.464 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.462 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.457 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.454 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.452 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.449 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.449 | |
| 4ejn | 0R4 | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.449 | |
| 3bhr | THG | Thymidylate synthase | / | 0.447 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.447 | |
| 2y46 | MIV | Mycinamicin IV hydroxylase/epoxidase | / | 0.446 | |
| 3h1j | SMA | Cytochrome b | / | 0.446 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.446 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.445 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.445 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.445 | |
| 1ot7 | CHC | Bile acid receptor | / | 0.444 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.444 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.444 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.444 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.443 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.443 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3p6n | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.440 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.440 |