sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 1.000 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.673 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.472 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.464 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.458 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.454 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.451 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.451 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.451 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 2rl1 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.443 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.443 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.443 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.443 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.440 |