sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 1.000 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.584 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.577 | |
| 1knr | FAD | L-aspartate oxidase | 1.4.3.16 | 0.513 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.493 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.492 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.491 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.485 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.482 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.481 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.464 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.461 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.460 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.456 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.456 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.454 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.451 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.450 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.450 | |
| 4ysh | FAD | Glycine oxidase | / | 0.450 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.449 | |
| 4ap3 | FAD | Steroid monooxygenase | / | 0.449 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.448 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.448 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.447 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.445 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.445 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.444 | |
| 2bab | FAD | Putative aminooxidase | / | 0.444 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.444 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.443 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.443 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.442 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.442 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.442 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.441 | |
| 5cku | FAD | L-ornithine N(5)-monooxygenase | / | 0.441 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.440 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.440 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.440 |