Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4xzm NAP Aldo-keto reductase family 1 member B10 1.1.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4xzm NAPAldo-keto reductase family 1 member B10 1.1.1 1.376
4xzn NAPAldo-keto reductase family 1 member B10 1.1.1 1.287
1c9w NAPAldose reductase-related protein 2 / 1.084
3qkz NAPAldose reductase-related protein 1 1.1.1.21 1.073
1ah4 NAPAldose reductase 1.1.1.21 1.068
1hqt NAPAlcohol dehydrogenase [NADP(+)] 1.1.1.2 1.062
2iq0 NAPAldose reductase 1.1.1.21 1.048
2j8t NAPAldose reductase 1.1.1.21 1.044
1z8a NAPAldose reductase 1.1.1.21 1.043
1x98 NAPAldose reductase 1.1.1.21 1.028
2pev NDPAldose reductase 1.1.1.21 1.027
2pf8 NDPAldose reductase 1.1.1.21 1.024
1ef3 NAPAldose reductase 1.1.1.21 1.008
2acq NAPAldose reductase 1.1.1.21 0.992
1x96 NAPAldose reductase 1.1.1.21 0.990
3v36 NAPAldose reductase 1.1.1.21 0.990
1ads NAPAldose reductase 1.1.1.21 0.988
3q67 NAPAldose reductase 1.1.1.21 0.979
2acu NAPAldose reductase 1.1.1.21 0.977
5c7h NDPPutative oxidoreductase / 0.925
3o3r NAPAldose reductase-related protein 1 1.1.1.21 0.900
2acs NAPAldose reductase 1.1.1.21 0.890
1vp5 NAPOxidoreductase, aldo/keto reductase family / 0.889
4g5d NDPProstaglandin F synthase 1.1.1.188 0.888
3h7u NAPNADPH-dependent aldo-keto reductase, chloroplastic / 0.887
4pmj NAPPutative oxidoreductase / 0.884
4jtq NAPAldo-keto reductase family 1 member C2 / 0.862
3q65 NAPAldose reductase 1.1.1.21 0.860
1az2 NAPAldose reductase 1.1.1.21 0.857
3dop NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.854
3caq NDP3-oxo-5-beta-steroid 4-dehydrogenase / 0.839
2hdj NDPAldo-keto reductase family 1 member C2 / 0.838
1k8c NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.837
3bv7 NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.834
3buv NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.833
1r38 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.828
4jq3 NAPAldo-keto reductase family 1 member C2 / 0.820
4ijr NDPD-arabinose dehydrogenase [NAD(P)+] heavy chain 1.1.1.117 0.819
3g1r NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.816
3wbw NDPPutative 2,5-diketo-D-gluconic acid reductase / 0.805
1q5m NDPProstaglandin-E(2) 9-reductase 1.1.1.189 0.802
4dz5 NAPAldo-keto reductase family 1 member C3 / 0.798
4xo7 NAPAldo-keto reductase family 1 member C2 / 0.798
1a80 NDP2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.793
4l1x NAPAldo-keto reductase family 1 member C2 / 0.789
2pfh NDPAldose reductase 1.1.1.21 0.788
2bgs NDPAldose reductase 1.1.1.21 0.782
2vdg NDPAldose reductase 1.1.1.21 0.782
3h7r NAPAldo-keto reductase family 4 member C8 / 0.778
1sm9 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.776
1m9h NAD2,5-diketo-D-gluconic acid reductase A 1.1.1.346 0.772
3wcz NAPAldo-keto reductase AKR2E4 / 0.758
2r9r NAPVoltage-gated potassium channel subunit beta-2 / 0.757
3uzw NAP3-oxo-5-beta-steroid 4-dehydrogenase / 0.757
1z9a NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.754
4jta NAPVoltage-gated potassium channel subunit beta-2 / 0.753
1mi3 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.750
2fvl NAPAldo-keto reductase family 1 member C4 1.1.1.225 0.750
1ye6 NAPNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.712
2c91 NAPAflatoxin B1 aldehyde reductase member 2 / 0.707
1ye6 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.704
4h8n NDPNADPH-dependent conjugated polyketone reductase C2 / 0.702
4aub NAPL-glyceraldehyde 3-phosphate reductase 1.1.1 0.696
1ye4 NADNAD(P)H-dependent D-xylose reductase 1.1.1.307 0.685
1s1p NAPAldo-keto reductase family 1 member C3 / 0.684
1lqa NDPProtein tas / 0.669
1lwi NAP3-alpha-hydroxysteroid dehydrogenase 1.1.1.50 0.668
1s1r NAPAldo-keto reductase family 1 member C3 / 0.668
1zgd NAPChalcone reductase / 0.666
2p5n NDPAldo-keto reductase family 1 member C21 1.1.1 0.665
2hej NDPAldo-keto reductase family 1 member C21 1.1.1 0.658