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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l6s 1WQ Poly [ADP-ribose] polymerase 1 2.4.2.30

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4l6s 1WQPoly [ADP-ribose] polymerase 1 2.4.2.30 0.938
4pnr G18Tankyrase-2 2.4.2.30 0.717
4avw G18Tankyrase-2 2.4.2.30 0.710
4avu LDRTankyrase-2 2.4.2.30 0.704
4hhz 15SPoly [ADP-ribose] polymerase 1 2.4.2.30 0.680
4pnm NU1Tankyrase-2 2.4.2.30 0.670
4j21 AJ6Tankyrase-2 2.4.2.30 0.663
4j3m AJ8Tankyrase-2 2.4.2.30 0.662
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.660
4e5i 0N9Polymerase acidic protein / 0.660
4bud 29FTankyrase-2 2.4.2.30 0.659
4iue AJ4Tankyrase-2 2.4.2.30 0.659
4j3l AJ5Tankyrase-2 2.4.2.30 0.656
4e5f 0N7Polymerase acidic protein / 0.654
5dsy UHBPoly [ADP-ribose] polymerase 2 2.4.2.30 0.653