sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4l4x | NDP | AmphI |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4l4x | NDP | AmphI | / | 1.448 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.810 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.761 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.758 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.735 | |
| 3mje | NDP | AmphB | / | 0.735 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.729 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.729 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.728 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.710 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.704 | |
| 1pt9 | TAP | NAD(P) transhydrogenase, mitochondrial | 1.6.1.2 | 0.701 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.701 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.697 | |
| 4hxy | NDP | Plm1 | / | 0.697 | |
| 4j16 | NAP | NAD(P) transhydrogenase subunit beta | / | 0.696 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.695 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.693 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.692 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.688 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.688 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.687 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.686 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.685 | |
| 1nm5 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.684 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.682 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.682 | |
| 5d2e | NAP | MlnE | / | 0.682 | |
| 1djl | NAP | NAD(P) transhydrogenase, mitochondrial | 1.6.1.2 | 0.681 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.681 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.679 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.678 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.678 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.678 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.677 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.676 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.676 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.676 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.675 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.675 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.675 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.674 | |
| 2cvu | CDP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.673 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.672 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.672 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.671 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.670 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.669 | |
| 3e8x | NAP | BH1520 protein | / | 0.668 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.667 | |
| 5aq1 | NDP | Glucose-6-phosphate 1-dehydrogenase | / | 0.666 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.665 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.665 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.665 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.664 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.662 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.662 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.660 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.659 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.659 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.658 | |
| 3uce | NDP | Dehydrogenase | / | 0.656 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.656 | |
| 3rv3 | ADP | Biotin carboxylase | 6.3.4.14 | 0.655 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.654 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.653 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.653 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.652 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.652 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.652 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.652 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.652 | |
| 4hs4 | FMN | Chromate reductase | / | 0.652 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.651 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.651 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.651 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.650 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.650 |