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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jrn ANP Rhoptry kinase family protein

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jrn ANPRhoptry kinase family protein / 0.912
2pul ACPMethylthioribose kinase 2.7.1.100 0.713
3llt ANPProtein serine/threonine kinase-1 / 0.711
2pz5 ACPFibroblast growth factor receptor 2 / 0.707
2pzp ACPFibroblast growth factor receptor 2 / 0.707
2py3 ACPFibroblast growth factor receptor 2 / 0.706
1j7u ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.704
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.701
3eth ATPN5-carboxyaminoimidazole ribonucleotide synthase / 0.698
5l8l ADPAurora kinase A 2.7.11.1 0.698
3orm AGSSerine/threonine protein kinase / 0.696
4ceg ADPAurora kinase A 2.7.11.1 0.696
3tm0 ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.694
3c4w ATPRhodopsin kinase / 0.693
3t8o ATPRhodopsin kinase / 0.693
4o4d ATPKinase / 0.688
3igo ANPCalmodulin-domain protein kinase 1, putative / 0.684
3ori AGSSerine/threonine protein kinase / 0.684
4ic7 ANPMitogen-activated protein kinase 7 2.7.11.24 0.683
3dnt ATPSerine/threonine-protein kinase toxin HipA / 0.678
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.677
3qc9 ADPRhodopsin kinase / 0.676
4fg7 ATPCalcium/calmodulin-dependent protein kinase type 1 2.7.11.17 0.675
1u54 ACPActivated CDC42 kinase 1 / 0.672
1w2c ANPInositol-trisphosphate 3-kinase A 2.7.1.127 0.671
3oro AGSSerine/threonine protein kinase / 0.671
3ort AGSSerine/threonine protein kinase / 0.671
2w4k ADPDeath-associated protein kinase 1 2.7.11.1 0.670
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.670
3fjq ATPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.670
3nyn SGVG protein-coupled receptor kinase 6 2.7.11.16 0.669
3orp AGSSerine/threonine protein kinase / 0.668
1jkl ANPDeath-associated protein kinase 1 2.7.11.1 0.667
3fhi ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.667
4ct2 ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.667
3c4x ATPRhodopsin kinase / 0.664
4nif ANPMitogen-activated protein kinase 1 2.7.11.24 0.664
4dg3 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
3c50 ADPRhodopsin kinase / 0.659
4azw ATPO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.659
2dwb ANPAurora kinase A 2.7.11.1 0.657
3bu5 ATPInsulin receptor 2.7.10.1 0.657
4c3r ACPAurora kinase A 2.7.11.1 0.655
3tpt ADPSerine/threonine-protein kinase toxin HipA / 0.654
4c5c ATPD-alanine--D-alanine ligase B 6.3.2.4 0.654
4f1m ACPProbable serine/threonine-protein kinase roco4 2.7.11.1 0.654
4eom ATPCyclin-dependent kinase 2 2.7.11.22 0.653
3akk ADPSerine/threonine-protein kinase CtkA 2.7.11.1 0.652
3f5u ANPDeath-associated protein kinase 1 2.7.11.1 0.652
3gu4 ANPDeath-associated protein kinase 1 2.7.11.1 0.650
3mfs ANPPeripheral plasma membrane protein CASK 2.7.11.1 0.650
4dh7 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.650
4eoo ATPCyclin-dependent kinase 2 2.7.11.22 0.650
4oau ADP2-5A-dependent ribonuclease 3.1.26 0.650