Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4im2 BX7 Serine/threonine-protein kinase TBK1 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4im2 BX7Serine/threonine-protein kinase TBK1 2.7.11.1 0.929
4im0 1FVSerine/threonine-protein kinase TBK1 2.7.11.1 0.745
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
1m3q ANGN-glycosylase/DNA lyase 3.2.2 0.744
1v2h GUNPurine nucleoside phosphorylase 2.4.2.1 0.744
2puc GUNHTH-type transcriptional repressor PurR / 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.744
4bbf O19Tyrosine-protein kinase JAK2 / 0.708
4eut BX7Serine/threonine-protein kinase TBK1 2.7.11.1 0.702
4iwo 1H4Serine/threonine-protein kinase TBK1 2.7.11.1 0.702
3uo5 0BXAurora kinase A 2.7.11.1 0.701
4iwq 1FVSerine/threonine-protein kinase TBK1 2.7.11.1 0.684
3uli 1N3Cyclin-dependent kinase 2 2.7.11.22 0.679
1oec AA2Fibroblast growth factor receptor 2 / 0.660
1ozq PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1p0e PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
1ulb GUNPurine nucleoside phosphorylase 2.4.2.1 0.660
2pot GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2pwu GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
2z1x PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
3bld PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4gcx PRFQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4h7z GUNQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hqv QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4hvx QEIQueuine tRNA-ribosyltransferase 2.4.2.29 0.660
4fsr HKCSerine/threonine-protein kinase Chk1 2.7.11.1 0.655
4dea NHIAurora kinase A 2.7.11.1 0.653
2j9m PY8Cyclin-dependent kinase 2 2.7.11.22 0.651