Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4f09 JAK Tyrosine-protein kinase JAK2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4f09 JAKTyrosine-protein kinase JAK2 / 0.861
4f08 1RSTyrosine-protein kinase JAK2 / 0.773
4ivd 15TTyrosine-protein kinase JAK1 / 0.764
4ivc 1J6Tyrosine-protein kinase JAK1 / 0.762
4ivb 1J5Tyrosine-protein kinase JAK1 / 0.761
4e5i 0N9Polymerase acidic protein / 0.744
4iva 1J5Tyrosine-protein kinase JAK2 / 0.743
4e4l 0NHTyrosine-protein kinase JAK1 / 0.741
4ei4 0Q2Tyrosine-protein kinase JAK1 / 0.734
4e6d 0NUTyrosine-protein kinase JAK2 / 0.694
4ehz JAKTyrosine-protein kinase JAK1 / 0.674
2ym3 YM3Serine/threonine-protein kinase Chk1 2.7.11.1 0.671
4e5f 0N7Polymerase acidic protein / 0.660
4fk6 0UJTyrosine-protein kinase JAK1 / 0.656
3zls 92PDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.655
4e6q 0NVTyrosine-protein kinase JAK2 / 0.655
1jpa ANPEphrin type-B receptor 2 2.7.10.1 0.651