Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4eqe KAA Histidine triad nucleotide-binding protein 1 3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4eqe KAAHistidine triad nucleotide-binding protein 1 3 1.024
4eqg A5AHistidine triad nucleotide-binding protein 1 3 1.016
1rzy 5ASHistidine triad nucleotide-binding protein 1 3 0.880
3n1s 5GPPurine nucleoside phosphoramidase / 0.831
5i2f BS5Histidine triad nucleotide-binding protein 1 3 0.830
4egu 5GPPutative histidine triad (HIT) protein / 0.797
3n1t 5GPPurine nucleoside phosphoramidase / 0.757
1xmm M7Gm7GpppX diphosphatase 3.6.1.59 0.724
3oxk 5GPHistidine triad nucleotide-binding protein 3 0.713
5fit AP2Bis(5'-adenosyl)-triphosphatase 3.6.1.29 0.692
3qgz ADNHistidine triad nucleotide-binding protein 1 3 0.691
1st0 GTGm7GpppX diphosphatase 3.6.1.59 0.679
3bgi SAHThiopurine S-methyltransferase 2.1.1.67 0.677
2bzg SAHThiopurine S-methyltransferase 2.1.1.67 0.672
5fa5 MTAProtein arginine N-methyltransferase 5 / 0.670
4iv8 SAMPhosphoethanolamine N-methyltransferase,putative / 0.663
2h39 ADQADP-glucose phosphorylase / 0.660
3nn6 FB06-hydroxy-L-nicotine oxidase / 0.659
4mb2 ATPUncharacterized protein / 0.659
1kvr NADUDP-glucose 4-epimerase 5.1.3.2 0.658
1rp0 AHZThiamine thiazole synthase, chloroplastic / 0.657
3a26 MTAtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.657
4ckb SAHmRNA-capping enzyme catalytic subunit 2.1.1.56 0.657
5e9w SAHmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.657
5je4 SAHMethyl transferase / 0.656
4ckc SAHmRNA-capping enzyme catalytic subunit 2.1.1.56 0.654
2p35 SAHTrans-aconitate 2-methyltransferase / 0.652
3ldf SAHUncharacterized protein / 0.650
4xba GMPAprataxin-like protein 3 0.650