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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3vs4 VSF Tyrosine-protein kinase HCK 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3vs4 VSFTyrosine-protein kinase HCK 2.7.10.2 1.140
3vs3 VSETyrosine-protein kinase HCK 2.7.10.2 1.027
3vry B43Tyrosine-protein kinase HCK 2.7.10.2 0.995
3vs5 VSGTyrosine-protein kinase HCK 2.7.10.2 0.927
2c0i L1GTyrosine-protein kinase HCK 2.7.10.2 0.864
2c0o L2GTyrosine-protein kinase HCK 2.7.10.2 0.856
1qcf PP1Tyrosine-protein kinase HCK 2.7.10.2 0.846
2c0t L3GTyrosine-protein kinase HCK 2.7.10.2 0.828
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4k11 0J9Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.735
1yol S03Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.733
2zv9 PP2Tyrosine-protein kinase Lyn 2.7.10.2 0.722
3vs7 KS1Tyrosine-protein kinase HCK 2.7.10.2 0.711
3vs1 VSATyrosine-protein kinase HCK 2.7.10.2 0.704
4mxa BK7Calmodulin-like domain protein kinase isoenzyme gamma, related / 0.697
4d9t 0JGRibosomal protein S6 kinase alpha-3 2.7.11.1 0.676
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.671
3l8p 0CEAngiopoietin-1 receptor 2.7.10.1 0.670
5ar4 SB2Receptor-interacting serine/threonine-protein kinase 2 2.7.11.1 0.669
1qpe PP2Tyrosine-protein kinase Lck 2.7.10.2 0.664
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.663
4e5f 0N7Polymerase acidic protein / 0.660
3w2s W2REpidermal growth factor receptor 2.7.10.1 0.652
1xxj UNCUricase 1.7.3.3 0.651
3vs0 VS0Tyrosine-protein kinase HCK 2.7.10.2 0.651
3vs6 VSHTyrosine-protein kinase HCK 2.7.10.2 0.651