Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3pqf NAD L-lactate dehydrogenase 1.1.1.27

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
3pqf NADL-lactate dehydrogenase 1.1.1.27 0.922
2e37 NADL-lactate dehydrogenase / 0.715
1il0 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.707
2g5c NADPrephenate dehydrogenase / 0.703
1dss NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.697
3nt4 NAIInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.697
4o63 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.695
2voj NADAlanine dehydrogenase 1.4.1.1 0.689
4xwz FADFructosyl amine:oxygen oxidoreductase / 0.688
1f0y NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.687
1szj NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.687
1guy NADMalate dehydrogenase / 0.686
1m76 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.686
3pym NADGlyceraldehyde-3-phosphate dehydrogenase 3 1.2.1.12 0.686
5c7o NADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific 1.2.1.12 0.686
3adp NAILambda-crystallin 1.1.1.45 0.684
4njo NADD-3-phosphoglycerate dehydrogenase, putative / 0.684
1f8f NADBenzyl alcohol dehydrogenase / 0.679
1vsv NADGlyceraldehyde-3-phosphate dehydrogenase / 0.679
3wmx NADNAD dependent epimerase/dehydratase / 0.679
4o59 NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.679
3f3s NADLambda-crystallin homolog / 0.678
1hyh NADL-2-hydroxyisocaproate dehydrogenase / 0.677
2aa3 AP0L-lactate dehydrogenase / 0.677
3nt2 NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.676
3ggo NAIPrephenate dehydrogenase / 0.674
1uxj NADMalate dehydrogenase / 0.673
5lc1 NADL-threonine 3-dehydrogenase / 0.673
3cps NADGlyceraldehyde-3-phosphate dehydrogenase / 0.672
3gvi ADPMalate dehydrogenase / 0.672
3d64 NADAdenosylhomocysteinase / 0.671
3jyo NADQuinate/shikimate dehydrogenase (NAD(+)) / 0.671
5ig2 NADShort-chain dehydrogenase/reductase SDR / 0.671
2fze APRAlcohol dehydrogenase class-3 1.1.1.1 0.670
4xd2 NAIAlcohol dehydrogenase E chain 1.1.1.1 0.670
4xq9 NADHomospermidine synthase 2.5.1.44 0.669
2dc1 NADProbable L-aspartate dehydrogenase / 0.668
3cif NADGlyceraldehyde-3-phosphate dehydrogenase / 0.668
3n7u NADFormate dehydrogenase, chloroplastic/mitochondrial / 0.668
1ywg NADGlyceraldehyde-3-phosphate dehydrogenase / 0.667
3ec7 NADInositol 2-dehydrogenase / 0.667
4k28 NADShikimate dehydrogenase family protein / 0.667
1m75 NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.666
3ntq NADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 1.1.1.18 0.666
1jki NAIInositol-3-phosphate synthase 5.5.1.4 0.665
1lld NADL-lactate dehydrogenase 2 1.1.1.27 0.665
1sc6 NADD-3-phosphoglycerate dehydrogenase 1.1.1.95 0.665
3keo NADRedox-sensing transcriptional repressor Rex / 0.665
3ket NADRedox-sensing transcriptional repressor Rex / 0.665
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.665
4ng5 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.665
4xgi NADGlutamate dehydrogenase / 0.665
1e3s NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.664
2npx NADNADH peroxidase 1.11.1.1 0.664
3g5q FADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO / 0.664
4z0h NADGlyceraldehyde-3-phosphate dehydrogenase GAPC1, cytosolic 1.2.1.12 0.664
5kcp NAJAlcohol dehydrogenase E chain 1.1.1.1 0.664
1mgo NADAlcohol dehydrogenase E chain 1.1.1.1 0.663
2ome NADC-terminal-binding protein 2 / 0.663
4dxh NAJAlcohol dehydrogenase E chain 1.1.1.1 0.663
5cdg NAJAlcohol dehydrogenase E chain 1.1.1.1 0.663
5kj1 NAJAlcohol dehydrogenase E chain 1.1.1.1 0.663
1f17 NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial 1.1.1.35 0.662
1u8f NADGlyceraldehyde-3-phosphate dehydrogenase 1.2.1.12 0.662
3ikt NADRedox-sensing transcriptional repressor Rex / 0.661
1bw9 NADPhenylalanine dehydrogenase / 0.659
1zmd NAIDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.659
4y9d NAIC alpha-dehydrogenase / 0.659
1pjc NADAlanine dehydrogenase / 0.656
1u1i NADMyo-inositol-1-phosphate synthase (Ino1) / 0.656
2gdz NAD15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.1.1.141 0.656
4cuk NAID-lactate dehydrogenase / 0.656
2hu2 NADC-terminal binding protein 1 / 0.655
3ids NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal 1.2.1.12 0.655
3cos NADAlcohol dehydrogenase 4 1.1.1.1 0.654
4tvb NADHomospermidine synthase 2.5.1.44 0.653
1ur5 NADMalate dehydrogenase / 0.652
1c1d NAIPhenylalanine dehydrogenase / 0.651
1gz4 ATPNAD-dependent malic enzyme, mitochondrial 1.1.1.38 0.651
2vyv NADGlyceraldehyde-3-phosphate dehydrogenase A / 0.650
3pvz NADUDP-N-acetylglucosamine 4,6-dehydratase / 0.650
3uko NADAlcohol dehydrogenase class-3 / 0.650