Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3em4 DR7 Gag-Pol polyprotein 3.4.23.16

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3em4 DR7Gag-Pol polyprotein 3.4.23.16 1.513
3eky DR7Gag-Pol polyprotein 3.4.23.16 1.249
3el1 DR7Gag-Pol polyprotein 3.4.23.16 1.202
3el9 DR7Gag-Pol polyprotein 3.4.23.16 1.172
2aqu DR7Gag-Pol polyprotein 3.4.23.16 1.150
3oxx DR7Gag-Pol polyprotein 3.4.23.16 1.137
2fxe DR7Gag-Pol polyprotein 3.4.23.16 1.112
2fxd DR7Pol polyprotein / 1.028
3gga GGWGag-Pol polyprotein / 0.984
3ekw DR7Gag-Pol polyprotein 3.4.23.16 0.975
1hih C20Gag-Pol polyprotein / 0.956
3kfn 3TLGag-Pol polyprotein / 0.936
2q54 MU1Protease / 0.901
3kfr 3TLGag-Pol polyprotein / 0.901
3sab F78Protease / 0.888
2qi5 MZ7Gag-Pol polyprotein / 0.886
1hii C20Gag-Pol polyprotein / 0.884
3nwq 2NCGag-Pol polyprotein 3.4.23.16 0.883
1izh Q50Protease / 0.881
3s85 LK0Gag-Pol polyprotein / 0.871
4kb9 G79Protease / 0.870
3vf7 031Gag-Pol polyprotein 3.4.23.16 0.868
3i2l 2NCProtease / 0.863
1fej 2NCGag-Pol polyprotein 3.4.23.16 0.855
1hos PHPGag-Pol polyprotein / 0.854
3kf0 3TLGag-Pol polyprotein / 0.853
2a1e IPFGag-Pol polyprotein 3.4.23.16 0.850
3sa7 55AProtease / 0.850
1ff0 2NCGag-Pol polyprotein 3.4.23.16 0.849
2qhy MZ1Gag-Pol polyprotein / 0.845
3pwm 017Gag-Pol polyprotein 3.4.23.16 0.843
2qci 065Gag-Pol polyprotein 3.4.23.16 0.842
3sa9 A68Protease / 0.840
3em3 478Gag-Pol polyprotein 3.4.23.16 0.837
2qi0 MZ3Gag-Pol polyprotein / 0.833
3slz 3TLPutative gag-pro-pol polyprotein / 0.832
2aoe 0Q4Gag-Pol polyprotein 3.4.23.16 0.829
3qaa G04Gag-Pol polyprotein 3.4.23.16 0.828
1fgc 2NCGag-Pol polyprotein 3.4.23.16 0.825
1z1h HBBGag-Pol polyprotein 3.4.23.16 0.825
1ffi 2NCGag-Pol polyprotein 3.4.23.16 0.824
3nxe 2NCProtease / 0.824
4djo MK5Pol polyprotein / 0.823
1hvl A76Gag-Pol polyprotein / 0.822
1hvj A78Gag-Pol polyprotein / 0.820
3bxr DRRGag-Pol polyprotein 3.4.23.16 0.820
3o9h K2EGag-Pol polyprotein / 0.820
1hvs A77Gag-Pol polyprotein / 0.818
4djp M73Pol polyprotein / 0.817
3kfs 3TLGag-Pol polyprotein / 0.815
1k1u 0Q4Gag-Pol polyprotein 3.4.23.16 0.814
3dck KVIProtease / 0.814
4hdp G52Gag-Pol polyprotein 3.4.23.16 0.814
4k4p 3TLGag-Pol polyprotein / 0.812
2qd8 065Gag-Pol polyprotein 3.4.23.16 0.810
1sdt MK1Gag-Pol polyprotein 3.4.23.16 0.808
3st5 G89Gag-Pol polyprotein 3.4.23.16 0.808
1hvi A77Protease / 0.806
3ok9 G52Gag-Pol polyprotein 3.4.23.16 0.806
2p3b 3TLV-1 PROTEASE protein / 0.805
2p3b 3TLV-1 protease / 0.805
2rkf AB1Pol protein / 0.805
1a8g 2Z4Gag-Pol polyprotein 3.4.23.16 0.804
2cem 2AHPol protein / 0.803
1tcx IM1Gag-Pol polyprotein 3.4.23.16 0.799
3ecg 065Gag-Pol polyprotein 3.4.23.47 0.799
3lzv 017Gag-Pol polyprotein 3.4.23.16 0.799
2i4x KGQProtease / 0.798
3o9f K2DGag-Pol polyprotein / 0.798
4q1w 017Gag-Pol polyprotein 3.4.23.16 0.798
1k2b 0Q4Gag-Pol polyprotein 3.4.23.16 0.797
3sa3 23XProtease / 0.797
3toh 079Gag-Pol polyprotein 2.7.7.49 0.797
2f81 017Gag-Pol polyprotein 3.4.23.16 0.796
3dcr KVSProtease / 0.796
4dqe 017Gag-Pol polyprotein / 0.796
3o9d K19Pol polyprotein / 0.795
3sa5 A69Protease / 0.795
2i4w KGQProtease / 0.793
3o99 K13Pol polyprotein / 0.793
3o9a K14Pol polyprotein / 0.793
3tof 076Gag-Pol polyprotein 2.7.7.49 0.793
3vfb 031Gag-Pol polyprotein 3.4.23.16 0.793
2ien 017Gag-Pol polyprotein 3.4.23.16 0.792
2avm 2NCGag-Pol polyprotein 3.4.23.16 0.791
3bvb 017Gag-Pol polyprotein 3.4.23.16 0.791
4dqc 017Gag-Pol polyprotein / 0.791
2f3k RO1Protease / 0.789
3hzc 2NCProtease / 0.789
4hdb G52Gag-Pol polyprotein 3.4.23.16 0.788
4q1x 017Gag-Pol polyprotein 3.4.23.16 0.788
3o9g F53Gag-Pol polyprotein / 0.786
1sbg IM1Gag-Pol polyprotein / 0.785
3k4v ROCGag-Pol polyprotein 3.4.23.16 0.785
2z4o 065Gag-Pol polyprotein 3.4.23.16 0.784
1fg6 2NCGag-Pol polyprotein 3.4.23.16 0.783
2fde 385Gag-Pol polyprotein 3.4.23.16 0.783
3o9i A61Gag-Pol polyprotein / 0.783
2psu MUUProtease / 0.781
3ndt ROCGag-Pol polyprotein 3.4.23.16 0.781
2hb3 GRLProtease / 0.780
2xyf G40Gag-Pol polyprotein / 0.780
3zpu M8BGag-Pol polyprotein 3.4.23.16 0.780
1hvk A79Gag-Pol polyprotein / 0.779
2cen 4AHProtease / 0.779
1ida 0POGag-Pol polyprotein 3.4.23.47 0.778
2cej 1AHPol protein / 0.777
3dk1 G05Gag-Pol polyprotein 3.4.23.16 0.777
3ekv 478Gag-Pol polyprotein 3.4.23.16 0.777
3vf5 031Gag-Pol polyprotein 3.4.23.16 0.777
3ndw RITGag-Pol polyprotein 3.4.23.16 0.776
2i0a MUIProtease / 0.774
3oxv 478Gag-Pol polyprotein 3.4.23.16 0.774
1t3r 017Gag-Pol polyprotein 3.4.23.16 0.773
4heg G52Gag-Pol polyprotein 3.4.23.16 0.773
4dqh 017Gag-Pol polyprotein / 0.772
2wkz 5AHGag-Pol polyprotein / 0.771
3d1z 017Gag-Pol polyprotein 3.4.23.16 0.770
3ggx GGXGag-Pol polyprotein / 0.770
1hiv 1ZKGag-Pol polyprotein / 0.769
2f80 017Gag-Pol polyprotein 3.4.23.16 0.769
2q5k AB1Protease / 0.769
2qd6 065Gag-Pol polyprotein 3.4.23.16 0.769
3gi4 K60Gag-Pol polyprotein / 0.769
3vfa 031Gag-Pol polyprotein 3.4.23.16 0.769
1ody LP1Gag-Pol polyprotein 3.4.23.16 0.768
1sdv MK1Gag-Pol polyprotein 3.4.23.16 0.767
2p3c 3TLProtease / 0.767
3ucb 017Gag-Pol polyprotein / 0.767
2xye CXGGag-Pol polyprotein / 0.766
3djk G55Gag-Pol polyprotein 3.4.23.16 0.765
2i4d QFIProtease / 0.764
1a94 0Q4Gag-Pol polyprotein 3.4.23.16 0.763
1rl8 RITGag-Pol polyprotein 3.4.23.16 0.761
2b60 RITPol polyprotein / 0.761
3i6o GR6Gag-Pol polyprotein 3.4.23.16 0.760
3nu4 478Gag-Pol polyprotein 3.4.23.16 0.759
9hvp 0E9Gag-Pol polyprotein / 0.759
2p3a 3TLPol protein / 0.758
3o9b K2APol polyprotein / 0.758
4njt 017Protease / 0.757
3nuj 478Gag-Pol polyprotein 3.4.23.16 0.756
1d4l PI9Gag-Pol polyprotein 3.4.23.16 0.755
2z54 AB1Gag-Pol polyprotein 3.4.23.16 0.755
3sa4 F72Protease / 0.755
3d1x ROCGag-Pol polyprotein 3.4.23.16 0.754
3nu3 478Gag-Pol polyprotein 3.4.23.16 0.754
1hpx KNIGag-Pol polyprotein / 0.753
3o9e A60Pol polyprotein / 0.753
3oy4 017Gag-Pol polyprotein 3.4.23.16 0.753
4j55 031Gag-Pol polyprotein 3.4.23.16 0.753
4njv RITProtease / 0.753
4q1y 017Gag-Pol polyprotein 3.4.23.16 0.753
1dif A85Gag-Pol polyprotein / 0.751
3sa6 F71Protease / 0.751
3nu6 478Gag-Pol polyprotein 3.4.23.16 0.750
2rkg AB1Pol protein / 0.749
4dqb 017Gag-Pol polyprotein / 0.749
4j5j 478Gag-Pol polyprotein 3.4.23.16 0.749
3d20 017Gag-Pol polyprotein 3.4.23.16 0.747
4njs G08Protease / 0.747
1pro A88Gag-Pol polyprotein / 0.746
3r4b 74TGag-Pol polyprotein / 0.746
1k2c 0Q4Gag-Pol polyprotein 3.4.23.16 0.745
3nuo 478Gag-Pol polyprotein 3.4.23.16 0.745
4djr 0KJPol polyprotein / 0.745
2avs MK1Gag-Pol polyprotein 3.4.23.16 0.744
3ekx 1UNGag-Pol polyprotein 3.4.23.16 0.742
3sac AF8Protease / 0.742
1siv PSIGag-Pol polyprotein / 0.741
3gi6 D78Gag-Pol polyprotein / 0.741
3mws 017Pol protein / 0.741
3o9c K20Pol polyprotein / 0.741
2q55 MU0Protease / 0.740
3oxw 017Gag-Pol polyprotein 3.4.23.16 0.740
3fx5 KNIGag-Pol polyprotein 3.4.23.16 0.739
3zpt M8YGag-Pol polyprotein 3.4.23.16 0.739
1vik BAYGag-Pol polyprotein / 0.737
2nnk ROCProtease / 0.737
3s43 478Protease / 0.737
1hxb ROCGag-Pol polyprotein 3.4.23.16 0.736
1m0b 0ZQGag-Pol polyprotein 3.4.23.16 0.736
2idw 017Protease / 0.736
2p3d 3TLProtease / 0.734
3nu5 478Gag-Pol polyprotein 3.4.23.16 0.734
2q63 1UNGag-Pol polyprotein 3.4.23.16 0.733
3kdb 006Gag-Pol polyprotein 3.4.23.16 0.733
1bdr IM1Gag-Pol polyprotein 3.4.23.16 0.732
3lin E13Protease / 0.732
3sa8 K83Protease / 0.731
2psv MUVProtease / 0.730
3nyg 2NCGag-Pol polyprotein 3.4.23.16 0.729
4i8z G08Gag-Pol polyprotein 3.4.23.16 0.729
2hs1 017Protease / 0.728
3s54 017Protease / 0.728
1ebw BEIGag-Pol polyprotein 3.4.23.16 0.727
1n49 RITGag-Pol polyprotein 3.4.23.16 0.726
3t3c 017Gag-Pol polyprotein 3.4.23.16 0.726
3zps EQMGag-Pol polyprotein 3.4.23.16 0.726
2qhz MZ2Gag-Pol polyprotein / 0.725
3ec0 GRLGag-Pol polyprotein 3.4.23.47 0.725
3tog 079Gag-Pol polyprotein 2.7.7.49 0.725
3d1y ROCGag-Pol polyprotein 3.4.23.16 0.724
1d4i BEGGag-Pol polyprotein 3.4.23.16 0.723
3jvy 017Gag-Pol polyprotein 3.4.23.16 0.723
4rvj 478Protease / 0.723
2i4u DJRProtease / 0.720
3bva 2NCGag-Pol polyprotein 3.4.23.16 0.720
3ndx RITGag-Pol polyprotein 3.4.23.16 0.720
3pwr ROCGag-Pol polyprotein 3.4.23.16 0.720
3gi5 K62Gag-Pol polyprotein / 0.718
4dqf 017Gag-Pol polyprotein / 0.718
4qgi ROCGag-Pol polyprotein 3.4.23.16 0.718
2f8g 017Gag-Pol polyprotein 3.4.23.16 0.717
3liq E14Protease / 0.716
2wl0 5AHGag-Pol polyprotein / 0.715
1t7i 017Gag-Pol polyprotein 3.4.23.16 0.714
3el4 ROCGag-Pol polyprotein 3.4.23.16 0.714
1hsh MK1Gag-Pol polyprotein / 0.713
2qi7 MZ9Gag-Pol polyprotein / 0.713
1mtr PI6Gag-Pol polyprotein 3.4.23.16 0.712
1k6p XN3Gag-Pol polyprotein 3.4.23.16 0.710
3bxs DRSGag-Pol polyprotein 3.4.23.16 0.710
2nnp ROCProtease / 0.709
3a2o KNJGag-Pol polyprotein 3.4.23.16 0.708
3lit E15Protease / 0.708
1hvr XK2Gag-Pol polyprotein / 0.707
2pk6 O33V-1 protease / 0.707
3i7e DJRGag-Pol polyprotein / 0.707
3tl9 ROCGag-Pol polyprotein 3.4.23.16 0.707
2qhc AB1Protease / 0.706
1npv L27Gag-Pol polyprotein 3.4.23.16 0.704
2fdd 385Pol protein / 0.704
1vij BAYGag-Pol polyprotein / 0.703
3ggu 017Gag-Pol polyprotein 3.4.23.16 0.703
1jld 0PPGag-Pol polyprotein / 0.702
1zsr 0ZTGag-Pol polyprotein 3.4.23.16 0.702
4hla 017Gag-Pol polyprotein 3.4.23.16 0.702
2qd7 065Gag-Pol polyprotein 3.4.23.16 0.701
2pym 1UNGag-Pol polyprotein 3.4.23.16 0.700
3nwx KVSGag-Pol polyprotein 3.4.23.16 0.700
3s56 ROCProtease / 0.700
1izi Q50Gag-Pol polyprotein 3.4.23.16 0.699
1mrw K57Gag-Pol polyprotein 3.4.23.16 0.698
2i0d MUTProtease / 0.698
1hpv 478Gag-Pol polyprotein / 0.697
1kzk JE2Gag-Pol polyprotein 3.4.23.16 0.697
1mrx K57Gag-Pol polyprotein 3.4.23.16 0.697
2fmb LP1Reverse transcriptase / 0.696
2pk5 075Protease / 0.696
3tlh 3TLGag-Pol polyprotein 3.4.23.16 0.695
4djq M86Pol polyprotein / 0.695
1d4h BEHGag-Pol polyprotein 3.4.23.16 0.694
2i4v DJRV-1 protease / 0.694
2bpv 1INGag-Pol polyprotein 3.4.23.16 0.693
2hs2 017Protease / 0.692
2avv MK1Gag-Pol polyprotein 3.4.23.16 0.689
3jw2 017Gag-Pol polyprotein 3.4.23.16 0.689
2ieo 017Protease / 0.685
1ec2 BEJGag-Pol polyprotein 3.4.23.16 0.684
1ec3 MS3Gag-Pol polyprotein 3.4.23.16 0.683
1dmp DMQGag-Pol polyprotein 3.4.23.16 0.682
1hxw RITGag-Pol polyprotein / 0.682
2nmy ROCProtease / 0.681
2qi4 MZ6Gag-Pol polyprotein / 0.681
3mxd K53Gag-Pol polyprotein 3.4.23.16 0.681
3nu9 478Gag-Pol polyprotein 3.4.23.16 0.681
1bv9 XV6Gag-Pol polyprotein 3.4.23.16 0.680
1d4k PI8Gag-Pol polyprotein 3.4.23.16 0.680
1fmb HYBPol polyprotein / 0.679
1npa 3NHGag-Pol polyprotein 3.4.23.16 0.679
1npw LGZGag-Pol polyprotein 3.4.23.16 0.679
1hsg MK1Gag-Pol polyprotein / 0.678
1ebk 0Q4Gag-Pol polyprotein 3.4.23.16 0.677
3em6 017Gag-Pol polyprotein 3.4.23.16 0.676
1z1r HBHGag-Pol polyprotein 3.4.23.16 0.675
2fle AIProtease / 0.675
3el5 1UNGag-Pol polyprotein / 0.675
1b6l PI4Gag-Pol polyprotein 3.4.23.16 0.674
1ec1 BEEGag-Pol polyprotein 3.4.23.16 0.674
1t7j 478Gag-Pol polyprotein 3.4.23.16 0.674
3ufn ROCGag-Pol polyprotein / 0.674
4a6b QG8Gag-Pol polyprotein 3.4.23.16 0.674
4a6c QG9Gag-Pol polyprotein 3.4.23.16 0.674
2bqv A1AProtease / 0.673
2pyn 1UNGag-Pol polyprotein 3.4.23.16 0.673
2uy0 HV1Gag-Pol polyprotein 3.4.23.16 0.673
3ndu ROCGag-Pol polyprotein 3.4.23.16 0.673
2bpw 1INGag-Pol polyprotein 3.4.23.16 0.672
3lzu 017Gag-Pol polyprotein 3.4.23.16 0.672
1xl5 190Gag-Pol polyprotein 3.4.23.16 0.671
1fg8 0Q4Gag-Pol polyprotein 3.4.23.16 0.670
2q64 1UNGag-Pol polyprotein 3.4.23.16 0.670
3cyx ROCGag-Pol polyprotein 3.4.23.16 0.670
2az8 3TLGag-Pol polyprotein 3.4.23.16 0.669
3ttp 017Gag-Pol polyprotein 3.4.23.16 0.669
1odx 0E8Gag-Pol polyprotein 3.4.23.16 0.668
2qi6 MZ8Gag-Pol polyprotein / 0.668
3ekp 478Gag-Pol polyprotein 3.4.23.16 0.668
1bdq IM1Gag-Pol polyprotein 3.4.23.16 0.667
2pwr G4GGag-Pol polyprotein 3.4.23.16 0.666
3lix E17Protease / 0.666
4j54 G52Gag-Pol polyprotein 3.4.23.16 0.666
1sdu MK1Gag-Pol polyprotein 3.4.23.16 0.665
2bb9 AKCGag-Pol polyprotein 3.4.23.16 0.664
2bpx MK1Gag-Pol polyprotein 3.4.23.16 0.662
3kdd JZQGag-Pol polyprotein 3.4.23.16 0.661
3kfp 3TLGag-Pol polyprotein / 0.661
1qbu 846Gag-Pol polyprotein 3.4.23.16 0.660
3lzs 017Gag-Pol polyprotein 3.4.23.16 0.660
1a8k 0Q4Gag-Pol polyprotein 3.4.23.16 0.659
3jvw DMPGag-Pol polyprotein 3.4.23.16 0.658
1b11 3TLPol polyprotein / 0.657
3nls 016Gag-Pol polyprotein 3.4.23.16 0.657
2qi3 MZ5Gag-Pol polyprotein / 0.656
3cyw 017Gag-Pol polyprotein 3.4.23.16 0.656
1k6c MK1Gag-Pol polyprotein 3.4.23.16 0.655
1odw 0E8Gag-Pol polyprotein 3.4.23.16 0.655
4a4q UX9Pol protein / 0.655
1t7k BH0Gag-Pol polyprotein 3.4.23.16 0.652
2az9 3TLGag-Pol polyprotein 3.4.23.16 0.651
2bbb HH1Gag-Pol polyprotein 3.4.23.16 0.651
3mxe K54Gag-Pol polyprotein 3.4.23.16 0.650
3sm2 478Putative gag-pro-pol polyprotein / 0.650