Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2ydo ADN Adenosine receptor A2a

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2ydo ADNAdenosine receptor A2a / 0.967
4uhr NGIAdenosine receptor A2a / 0.869
3qak UKAAdenosine receptor A2a / 0.813
4ug2 NGIAdenosine receptor A2a / 0.793
5g53 NECAdenosine receptor A2a / 0.774
4y8v ADPAcyl-CoA synthetase (NDP forming) / 0.744
1l8t ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.700
1e79 ADPATP synthase subunit alpha, mitochondrial / 0.695
1e79 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.695
2jiz ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.693
2ioa ADPBifunctional glutathionylspermidine synthetase/amidase / 0.691
2b0q ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.683
1h8h ADPATP synthase subunit alpha, mitochondrial / 0.681
1h8h ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.681
3t9e ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.681
4ffl ADPUncharacterized protein / 0.679
4ffr ATPUncharacterized protein / 0.679
4c5b ADPD-alanine--D-alanine ligase B 6.3.2.4 0.676
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.675
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.675
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.674
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.674
1j7l ADPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.671
2d1t SLULuciferin 4-monooxygenase 1.13.12.7 0.670
2p0a ANPSynapsin-3 / 0.670
3oij SAHRibosomal RNA small subunit methyltransferase NEP1 / 0.670
3t9f ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.669
1v25 ANPLong-chain-fatty-acid--CoA ligase 6.2.1.3 0.668
4q4c ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.668
3i12 ADPD-alanine--D-alanine ligase A 6.3.2.4 0.667
1ses AHXSerine--tRNA ligase 6.1.1.11 0.666
5c3z ACPRibokinase / 0.666
1cgp CMPcAMP-activated global transcriptional regulator CRP / 0.665
4a2b AGSCell division protein FtsA / 0.665
4bgb ADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases / 0.665
3zkd ANPDNA gyrase subunit B / 0.664
4bw9 ANPPyrrolysine--tRNA ligase / 0.664
2x86 ADPADP-L-glycero-D-manno-heptose-6-epimerase / 0.661
1zs6 ADPNucleoside diphosphate kinase 3 2.7.4.6 0.660
1j7u ANPAminoglycoside 3'-phosphotransferase 2.7.1.95 0.659
2dxe GDPNucleoside diphosphate kinase 2.7.4.6 0.659
2zt5 B4PGlycine--tRNA ligase / 0.659
3wnz ADPAlanine--anticapsin ligase / 0.659
2pcm SAHDiphthine synthase / 0.657
2phk ATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2.7.11.19 0.657
2r7n ADP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase / 0.656
1s16 ANPDNA topoisomerase 4 subunit B / 0.655
3q1k ADPD-alanine--D-alanine ligase A 6.3.2.4 0.655
3s87 ADPRibonucleoside-diphosphate reductase large chain 1 1.17.4.1 0.655
4i0b CMPcAMP-activated global transcriptional regulator CRP / 0.655
5bsm ATP4-coumarate--CoA ligase 2 6.2.1.12 0.655
3tw6 ADPPyruvate carboxylase / 0.654
2e8s SAHDiphthine synthase / 0.653
4xeo A5AAlanine--tRNA ligase, cytoplasmic / 0.653
1ig1 ANPDeath-associated protein kinase 1 2.7.11.1 0.652
2ek4 SAHDiphthine synthase / 0.652
4hr2 ADPNucleoside diphosphate kinase / 0.652
4iaf ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.652
2zt7 ATPGlycine--tRNA ligase / 0.651
2q7h YLYPyrrolysine--tRNA ligase / 0.650
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.650
5c40 ACPRibokinase / 0.650