Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vgo AD5 Aurora kinase B-A 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2vgo AD5Aurora kinase B-A 2.7.11.1 0.804
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2itx ANPEpidermal growth factor receptor 2.7.10.1 0.684
3b2t M33Fibroblast growth factor receptor 2 / 0.680
2wms ZYSSerine/threonine-protein kinase Chk1 2.7.11.1 0.670
3qyw 6PBMitogen-activated protein kinase 1 2.7.11.24 0.668
4utd ACPAurora kinase A 2.7.11.1 0.666
2wmu ZYUSerine/threonine-protein kinase Chk1 2.7.11.1 0.664
5dt4 ATPAurora kinase A 2.7.11.1 0.664
4e5f 0N7Polymerase acidic protein / 0.660
5dnr ATPAurora kinase A 2.7.11.1 0.660
4j95 ACPFibroblast growth factor receptor 2 / 0.659
2eva ADNMitogen-activated protein kinase kinase kinase 7 2.7.11.25 0.657
4e6q 0NVTyrosine-protein kinase JAK2 / 0.657
4ogr ADNCyclin-dependent kinase 9 2.7.11.22 0.654
3ung ADPCRISPR system Cmr subunit Cmr2 / 0.653
4j98 ACPFibroblast growth factor receptor 2 / 0.650