sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ou2 | ACO | Histone acetyltransferase KAT5 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 1.377 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 1.053 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 1.004 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 1.002 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 1.002 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.974 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.966 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.947 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.939 | |
| 5h86 | BCO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.860 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.838 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.826 | |
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 0.807 | |
| 5h84 | 1VU | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.805 | |
| 1qsr | ACO | HAT A1 | / | 0.798 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.793 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.791 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.782 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.779 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.777 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.773 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.758 | |
| 1qsn | COA | HAT A1 | / | 0.755 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.753 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.746 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.746 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.740 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.740 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.737 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.736 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.736 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.729 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.729 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.726 | |
| 1pua | COA | HAT A1 | / | 0.725 | |
| 5ag6 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.725 | |
| 4gs4 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.720 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.720 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.719 | |
| 4xpd | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.719 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.718 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.717 | |
| 4if5 | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.717 | |
| 1cm0 | COA | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.713 | |
| 4u9v | ACO | N-alpha-acetyltransferase 40 | 2.3.1 | 0.713 | |
| 2vxk | COA | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.712 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.707 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.704 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.704 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.703 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.703 | |
| 2vbq | BSJ | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.699 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.698 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.698 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.696 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.696 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.691 | |
| 4cry | ACO | PanD regulatory factor | / | 0.691 | |
| 4crz | ACO | PanD regulatory factor | / | 0.688 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.685 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.685 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.684 | |
| 1s7n | COA | Acetyl transferase | / | 0.684 | |
| 3r95 | ACO | MccE protein | / | 0.684 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.684 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.683 | |
| 2wsa | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.680 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.679 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.678 | |
| 5ag4 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.678 | |
| 1p0h | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.677 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.677 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.677 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.674 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.671 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.668 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.668 | |
| 4kub | COA | Uncharacterized protein | / | 0.666 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.663 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.657 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.657 | |
| 1m1d | LYX | HAT A1 | / | 0.656 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.651 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.650 |