Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2hms NAI Ktr system potassium uptake protein A

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2hms NAIKtr system potassium uptake protein A / 1.030
3ou6 SAMSAM-dependent methyltransferase / 0.696
2hmv ADPKtr system potassium uptake protein A / 0.695
3tos SAHCalS11 / 0.695
4yuz S4MSpermidine synthase, putative / 0.694
5ccb SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.694
2vdv SAMtRNA (guanine-N(7)-)-methyltransferase / 0.688
3rfx NADUronate dehydrogenase / 0.688
1qao SAMrRNA adenine N-6-methyltransferase 2.1.1.184 0.687
2o07 MTASpermidine synthase 2.5.1.16 0.683
2qe6 SAMUncharacterized protein / 0.683
3a25 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.683
4gdp FADPolyamine oxidase FMS1 / 0.683
3bwc SAMSpermidine synthase, putative / 0.682
4gf5 SAHCalS11 / 0.681
5ccx SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.681
2p35 SAHTrans-aconitate 2-methyltransferase / 0.680
3a26 MTAtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.680
4y9d NAIC alpha-dehydrogenase / 0.680
4pyo SAHCatechol O-methyltransferase 2.1.1.6 0.679
3ldg SAHUncharacterized protein / 0.673
3pvz NADUDP-N-acetylglucosamine 4,6-dehydratase / 0.673
1jr4 CL4Catechol O-methyltransferase 2.1.1.6 0.672
5je4 SAHMethyl transferase / 0.672
1p1h NADInositol-3-phosphate synthase 5.5.1.4 0.671
2wsb NADGalactitol dehydrogenase / 0.669
3ou2 SAHSAM-dependent methyltransferase / 0.669
4iv0 SAMPhosphoethanolamine N-methyltransferase, putative / 0.669
3epp SFGmRNA cap guanine-N7 methyltransferase 2.1.1.56 0.668
3ou7 SAMSAM-dependent methyltransferase / 0.667
1y8q ATPSUMO-activating enzyme subunit 2 6.3.2 0.666
4azw SAMO-antigen chain terminator bifunctional methyltransferase/kinase WbdD / 0.666
3iv6 SAMUncharacterized protein / 0.665
4ymg SAMPutative SAM-dependent O-methyltranferase / 0.665
2np6 NEAModification methylase TaqI 2.1.1.72 0.664
2qa2 FADPolyketide oxygenase CabE / 0.664
1sqf SAMRibosomal RNA small subunit methyltransferase B 2.1.1.176 0.663
3lcc SAHThiocyanate methyltransferase 1 / 0.663
3sso SAHMycinamicin VI 2''-O-methyltransferase / 0.663
7mht SAHModification methylase HhaI 2.1.1.37 0.663
3uj8 SFGPhosphoethanolamine N-methyltransferase / 0.662
1d2h SAHGlycine N-methyltransferase 2.1.1.20 0.661
2uyh SAHModification methylase HhaI 2.1.1.37 0.661
2yqz SAMUncharacterized protein / 0.661
3c3y SAHO-methyltransferase / 0.660
4qdk SAHMagnesium-protoporphyrin O-methyltransferase 2.1.1.11 0.660
3he3 FADUDP-galactopyranose mutase / 0.657
3u81 SAHCatechol O-methyltransferase 2.1.1.6 0.657
4pyn SAHCatechol O-methyltransferase 2.1.1.6 0.657
3pgx NADUncharacterized NAD-dependent oxidoreductase MAP_4146 / 0.656
3qj4 FADRenalase / 0.656
4nbu NAI3-oxoacyl-(Acyl-carrier-protein) reductase / 0.655
1wg8 SAMRibosomal RNA small subunit methyltransferase H / 0.654
2nyu SAMrRNA methyltransferase 2, mitochondrial / 0.654
2oy0 SAHGenome polyprotein / 0.654
4mwz SAMPhosphoethanolamine N-methyltransferase, putative / 0.654
1h83 FADPolyamine oxidase 1.5.3.14 0.652
4nec SAHPutative SAM-dependent methyltransferase / 0.652
4yv2 S4MSpermidine synthase, putative / 0.652
1rjd SAMLeucine carboxyl methyltransferase 1 2.1.1.233 0.651
4mb2 ATPUncharacterized protein / 0.651
3ihg FADAklavinone 12-hydroxylase RdmE / 0.650
3rw9 DSHSpermidine synthase 2.5.1.16 0.650
4dcm SAMRibosomal RNA large subunit methyltransferase G 2.1.1.174 0.650