sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2fiw | ACO | GCN5-related N-acetyltransferase:Aminotransferase, class-II | / | 1.392 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.885 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.883 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.865 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.862 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.855 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.849 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.849 | |
| 2cnt | COA | Ribosomal-protein-alanine acetyltransferase | / | 0.837 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.836 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.829 | |
| 3exn | ACO | Probable acetyltransferase | / | 0.828 | |
| 4r3k | COA | N-alpha-acetyltransferase | 2.3.1 | 0.828 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.811 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.807 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.806 | |
| 4kvx | ACO | N-terminal acetyltransferase A complex catalytic subunit ard1 | 2.3.1.88 | 0.800 | |
| 1tiq | COA | Spermidine/spermine N(1)-acetyltransferase | / | 0.792 | |
| 2rc4 | ACO | Histone acetyltransferase KAT6A | / | 0.791 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.785 | |
| 1bob | ACO | Histone acetyltransferase type B catalytic subunit | / | 0.778 | |
| 1pua | COA | HAT A1 | / | 0.778 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.776 | |
| 4zm6 | ACO | N-acetyl-beta-D glucosaminidase | / | 0.774 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.768 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.765 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.762 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.759 | |
| 1z4r | ACO | Histone acetyltransferase KAT2A | 2.3.1.48 | 0.759 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.759 | |
| 2jev | NHQ | Diamine acetyltransferase 1 | / | 0.746 | |
| 1j4j | ACO | Acetyltransferase | 2.3.1 | 0.744 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.742 | |
| 1qsm | ACO | Histone acetyltransferase HPA2 | / | 0.739 | |
| 1wwz | ACO | Uncharacterized protein | / | 0.738 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.738 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.735 | |
| 2x7b | COA | N-alpha-acetyltransferase | 2.3.1 | 0.731 | |
| 1pu9 | COA | HAT A1 | / | 0.730 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.728 | |
| 2cy2 | ACO | Probable acetyltransferase | / | 0.727 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.724 | |
| 2fxf | ACO | Diamine acetyltransferase 1 | / | 0.723 | |
| 2q4v | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.718 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.716 | |
| 4mxe | ACO | N-acetyltransferase ESCO1 | 2.3.1 | 0.716 | |
| 1kuv | CA5 | Serotonin N-acetyltransferase | / | 0.710 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.705 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.703 | |
| 3s6f | COA | Uncharacterized protein | / | 0.701 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.699 | |
| 1qsn | COA | HAT A1 | / | 0.698 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.696 | |
| 1m1d | LYX | HAT A1 | / | 0.693 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.687 | |
| 3r96 | ACO | MccE protein | / | 0.686 | |
| 1qsr | ACO | HAT A1 | / | 0.685 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.685 | |
| 4qvt | ACO | Acetyltransferase YpeA | 2.3.1 | 0.685 | |
| 1s60 | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.684 | |
| 2zw4 | COA | Bleomycin acetyltransferase | / | 0.683 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.683 | |
| 2zfn | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.675 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.675 | |
| 4b5p | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.675 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.674 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.672 | |
| 2bsw | CAO | Probable acetyltransferase | / | 0.671 | |
| 4ua3 | COA | N-alpha-acetyltransferase 40 | 2.3.1 | 0.671 | |
| 2bei | ACO | Diamine acetyltransferase 2 | 2.3.1.57 | 0.667 | |
| 4jwp | ACO | GCN5-related N-acetyltransferase | / | 0.667 | |
| 2o28 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.666 | |
| 1bo4 | COA | Aminoglycoside-(3)-N-acetyltransferase | / | 0.663 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.662 | |
| 2vez | ACO | Glucosamine 6-phosphate acetyltransferase, putative | / | 0.661 | |
| 3k9u | ACO | Spermidine N(1)-acetyltransferase | / | 0.659 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.657 | |
| 2zpa | ACO | tRNA(Met) cytidine acetyltransferase TmcA | / | 0.657 | |
| 5kf8 | COA | Predicted acetyltransferase | / | 0.657 |