sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2f1k | NAP | Prephenate dehydrogenase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2f1k | NAP | Prephenate dehydrogenase | / | 1.119 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.766 | |
| 1zh8 | NAP | Uncharacterized protein | / | 0.749 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.733 | |
| 3f3s | NAD | Lambda-crystallin homolog | / | 0.714 | |
| 5a02 | NAP | Glucose-fructose oxidoreductase | / | 0.713 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.710 | |
| 4om8 | NAD | 3-hydroxybutyryl-coA dehydrogenase | / | 0.707 | |
| 2glx | NDP | 1,5-anhydro-D-fructose reductase | / | 0.706 | |
| 2ixa | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.701 | |
| 2ixb | NAD | Alpha-N-acetylgalactosaminidase | 3.2.1.49 | 0.696 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.695 | |
| 3ggp | NAD | Prephenate dehydrogenase | / | 0.695 | |
| 4gae | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.694 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.691 | |
| 2g82 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.687 | |
| 2qx7 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.687 | |
| 1h6a | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.686 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.682 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.681 | |
| 1dss | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.679 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.679 | |
| 5a06 | NDP | Glucose-fructose oxidoreductase | / | 0.679 | |
| 5c7o | NAD | Glyceraldehyde-3-phosphate dehydrogenase, testis-specific | 1.2.1.12 | 0.678 | |
| 3rbv | NAP | Sugar 3-ketoreductase | / | 0.675 | |
| 1gd1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.674 | |
| 4k9d | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.673 | |
| 3cmc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.670 | |
| 1jn0 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.668 | |
| 1cf2 | NAP | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.666 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.666 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.665 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.665 | |
| 1lua | NAP | Bifunctional protein MdtA | 1.5.1.5 | 0.663 | |
| 5a04 | NDP | Glucose-fructose oxidoreductase | / | 0.663 | |
| 5a05 | NDP | Glucose-fructose oxidoreductase | / | 0.663 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.662 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.662 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.660 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.660 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.660 | |
| 1ryd | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.659 | |
| 1vsv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.659 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.659 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.659 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.658 | |
| 4lsm | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.658 | |
| 4p8r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.658 | |
| 3hja | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.656 | |
| 3nt2 | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.656 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.655 | |
| 4o63 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.655 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.655 | |
| 1dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.653 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.653 | |
| 3mje | NDP | AmphB | / | 0.653 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.653 | |
| 2r6j | NDP | Eugenol synthase 1 | 1.1.1.318 | 0.652 | |
| 3oa2 | NAD | UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase | / | 0.652 | |
| 3v1y | NAD | Glyceraldehyde-3-phosphate dehydrogenase 1, cytosolic | 1.2.1.12 | 0.651 | |
| 1nvm | NAD | Acetaldehyde dehydrogenase | 1.2.1.10 | 0.650 |