sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.971 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.766 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.729 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.728 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.724 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.715 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.707 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.706 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.701 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.701 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.695 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.692 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.691 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.688 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.688 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.688 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.688 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.687 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.686 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.685 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.685 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.677 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.677 | |
| 2p35 | SAH | Trans-aconitate 2-methyltransferase | / | 0.676 | |
| 2qe6 | SAM | Uncharacterized protein | / | 0.674 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.674 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.672 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.672 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.671 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.671 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.670 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.669 | |
| 2v7g | NAD | Urocanate hydratase | 4.2.1.49 | 0.668 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.668 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.664 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.664 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.663 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.663 | |
| 2np6 | NEA | Modification methylase TaqI | 2.1.1.72 | 0.662 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.662 | |
| 5je3 | SAH | Methyl transferase | / | 0.662 | |
| 1kia | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.661 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.661 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.660 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.660 | |
| 3tos | SAH | CalS11 | / | 0.660 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.659 | |
| 1ri3 | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.659 | |
| 4yv0 | S4M | Spermidine synthase, putative | / | 0.658 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.657 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.657 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.657 | |
| 4yuz | S4M | Spermidine synthase, putative | / | 0.657 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.656 | |
| 3epp | SFG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.656 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.656 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.654 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.653 | |
| 3bgv | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.653 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.652 | |
| 4iwn | GEK | Carboxy-S-adenosyl-L-methionine synthase | / | 0.652 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.651 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.650 | |
| 3g07 | SAM | 7SK snRNA methylphosphate capping enzyme | 2.1.1 | 0.650 | |
| 3ou6 | SAM | SAM-dependent methyltransferase | / | 0.650 |