Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2agt FID Aldose reductase 1.1.1.21

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
2agt FIDAldose reductase 1.1.1.21 0.825
2pdy FIDAldose reductase 1.1.1.21 0.776
2pdw FIDAldose reductase 1.1.1.21 0.775
1pwm FIDAldose reductase 1.1.1.21 0.766
3h4g FIDAlcohol dehydrogenase [NADP(+)] 1.1.1.2 0.755
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4gab FIDAldo-keto reductase family 1 member B10 1.1.1 0.741
2pd9 FIDAldose reductase 1.1.1.21 0.732
4ga8 SBIAldo-keto reductase family 1 member B10 1.1.1 0.718
1ef3 FIDAldose reductase 1.1.1.21 0.715
2pdk SBIAldose reductase 1.1.1.21 0.714
1ah0 SBIAldose reductase 1.1.1.21 0.694
4e5f 0N7Polymerase acidic protein / 0.660