Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1rl3 PCG cAMP-dependent protein kinase type I-alpha regulatory subunit

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1rl3 PCGcAMP-dependent protein kinase type I-alpha regulatory subunit / 0.919
3cl1 PCGCyclic nucleotide-gated potassium channel mll3241 / 0.744
1q43 CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / 0.732
1q3e PCGPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / 0.730
3bpz CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / 0.729
3ocp CMPcGMP-dependent protein kinase 1 2.7.11.12 0.721
1cx4 CMPcAMP-dependent protein kinase type II-beta regulatory subunit / 0.718
2ptm CMPHyperpolarization-activated (Ih) channel / 0.714
3u11 CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 / 0.711
5c8w PCGcGMP-dependent protein kinase 2 2.7.11.12 0.711
3otf CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 / 0.710
1rgs CMPcAMP-dependent protein kinase type I-alpha regulatory subunit / 0.708
4hbn CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 / 0.704
3u0z CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 / 0.702
4ku7 PCGcGMP-dependent protein kinase 1 2.7.11.12 0.702
1ne6 SP1cAMP-dependent protein kinase type I-alpha regulatory subunit / 0.701
1q5o CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / 0.700
4jv4 1ORcAMP-dependent protein kinase type I-alpha regulatory subunit / 0.700
5c6c CMPcGMP-dependent protein kinase 2 2.7.11.12 0.699
3shr CMPcGMP-dependent protein kinase 1 2.7.11.12 0.692
3n4m CMPcAMP-activated global transcriptional regulator CRP / 0.691
3of1 CMPcAMP-dependent protein kinase regulatory subunit / 0.691
1vp6 CMPCyclic nucleotide-gated potassium channel mll3241 / 0.689
3ogj CMPcGMP-dependent protein kinase 1 2.7.11.12 0.688
3u10 CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / 0.686
4mgk CMPRap guanine nucleotide exchange factor 4 / 0.686
4z07 PCGcGMP-dependent protein kinase 1 2.7.11.12 0.686
4qx5 CMPcGMP-dependent protein kinase 1 2.7.11.12 0.685
1g6n CMPcAMP-activated global transcriptional regulator CRP / 0.682
2cgp CMPcAMP-activated global transcriptional regulator CRP / 0.679
1zrd CMPcAMP-activated global transcriptional regulator CRP / 0.677
4n9i PCGCatabolite expression activator / 0.676
1zrc CMPcAMP-activated global transcriptional regulator CRP / 0.675
3od0 PCGcGMP-dependent protein kinase 1 2.7.11.12 0.675
1ne4 RP1cAMP-dependent protein kinase type I-alpha regulatory subunit / 0.668
4i09 CMPcAMP-activated global transcriptional regulator CRP / 0.668
2k0g CMPCyclic nucleotide-gated potassium channel mll3241 / 0.659
1ruo CMPcAMP-activated global transcriptional regulator CRP / 0.652