Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1n2e APC Pantothenate synthetase 6.3.2.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1n2e APCPantothenate synthetase 6.3.2.1 1.159
1n2g APCPantothenate synthetase 6.3.2.1 1.113
2a84 ATPPantothenate synthetase 6.3.2.1 1.053
3iob A4DPantothenate synthetase 6.3.2.1 0.788
3iod A6DPantothenate synthetase 6.3.2.1 0.773
3cow 52HPantothenate synthetase 6.3.2.1 0.760
3coy 53HPantothenate synthetase 6.3.2.1 0.751
3ioe A7DPantothenate synthetase 6.3.2.1 0.751
3ag6 PAJPantothenate synthetase / 0.746
3ioc A5DPantothenate synthetase 6.3.2.1 0.740
3coz 54HPantothenate synthetase 6.3.2.1 0.738
3qtt ANPPantothenate synthetase / 0.718
4fvq ATPTyrosine-protein kinase JAK2 / 0.704
1n75 ATPGlutamate--tRNA ligase 6.1.1.17 0.702
5i4n ATPTyrosine-protein kinase JAK2 / 0.700
4fvr ATPTyrosine-protein kinase JAK2 / 0.698
5hg0 SAMPantothenate synthetase / 0.693
5c03 AGSNon-receptor tyrosine-protein kinase TYK2 2.7.10.2 0.683
3ahj TPPProbable phosphoketolase / 0.676
2v9x DUTdCTP deaminase / 0.675
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.675
1oe0 TTPDeoxynucleoside kinase / 0.673
3ahi HTLProbable phosphoketolase / 0.669
3ahe THDProbable phosphoketolase / 0.667
3nd6 ATPPhosphopantetheine adenylyltransferase / 0.666
5erm 210Fusicoccadiene synthase 4.2.3.43 0.665
1xs4 DCPdCTP deaminase / 0.662
4fhp UTPTerminal uridylyltransferase cid1 / 0.662
5cns DATRibonucleoside-diphosphate reductase 1 subunit alpha 1.17.4.1 0.661
1mh1 GNPRas-related C3 botulinum toxin substrate 1 / 0.660
3qbt GNPRas-related protein Rab-8A / 0.660
2wow NDPTrypanothione reductase / 0.659
5byl GCPBifunctional AAC/APH 2.3.1 0.659
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.658
2x3f APCPantothenate synthetase / 0.658
3kt3 TYMTryptophan--tRNA ligase, cytoplasmic 6.1.1.2 0.658
3w2w ATPCRISPR system Cmr subunit Cmr2 / 0.658
4idp GNPAtlastin-1 3.6.5 0.658
4x3m ADNRNA 2'-O ribose methyltransferase / 0.657
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.655
3tkl GTPRas-related protein Rab-1A / 0.655
4a6a TTPdCTP deaminase 3.5.4.13 0.655
4ehu ANP2-hydroxyisocaproyl-CoA dehydratase activator / 0.655
1bh5 GTXLactoylglutathione lyase 4.4.1.5 0.653
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.653
3lfz ADPUncharacterized protein MJ1225 / 0.653
3m0e ATPTranscriptional regulator (NtrC family) / 0.652
3zcb ATPAdenosine monophosphate-protein transferase VbhT 2.7.7.n1 0.652
3zxi TYATyrosine--tRNA ligase, mitochondrial 6.1.1.1 0.651
1pk8 ATPSynapsin-1 / 0.650
4tv9 GTPTubulin alpha-1B chain / 0.650