Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1fxs NAP GDP-L-fucose synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
1fxs NAPGDP-L-fucose synthase / 1.194
1bsv NDPGDP-L-fucose synthase / 0.977
1bws NDPGDP-L-fucose synthase / 0.822
1e7q NAPGDP-L-fucose synthase / 0.809
1i36 NAPConserved protein / 0.697
3sxp NADADP-L-glycero-D-mannoheptose-6-epimerase / 0.692
3pdu NAPGlyoxalate/3-oxopropanoate/4-oxobutanoate reductase / 0.689
2pk3 A2RGDP-6-deoxy-D-mannose reductase / 0.686
4xqc NADHomospermidine synthase 2.5.1.44 0.685
4xrg NADHomospermidine synthase 2.5.1.44 0.685
4xq9 NADHomospermidine synthase 2.5.1.44 0.684
3uxy NADShort-chain dehydrogenase/reductase SDR / 0.671
1q0q NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase 1.1.1.267 0.670
2ydx NAPMethionine adenosyltransferase 2 subunit beta / 0.670
4hp8 NAP2-deoxy-D-gluconate 3-dehydrogenase / 0.670
2ggs NDPdTDP-4-dehydrorhamnose reductase / 0.668
1kc1 NDPdTDP-4-dehydrorhamnose reductase 1.1.1.133 0.667
4c7k NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.667
3iah NAPPutative oxoacyl-(Acyl carrier protein) reductase / 0.665
1rpn NDPGDP-mannose 4,6-dehydratase / 0.664
2g5c NADPrephenate dehydrogenase / 0.662
3keq NADRedox-sensing transcriptional repressor Rex / 0.661
4plp NADHomospermidine synthase 2.5.1.44 0.660
1zh8 NAPUncharacterized protein / 0.659
4e5p NADPhosphonate dehydrogenase 1.20.1.1 0.659
2yut NAPPutative short-chain oxidoreductase / 0.658
2q1u NADPutative nucleotide sugar epimerase/ dehydratase / 0.657
3pvz NADUDP-N-acetylglucosamine 4,6-dehydratase / 0.657
3jv7 NADSecondary alcohol dehydrogenase / 0.656
4hbg NDP3-oxoacyl-[acyl-carrier-protein] reductase 1.1.1.100 0.656
4o0l NDPNADPH-dependent 3-quinuclidinone reductase / 0.655
4tvb NADHomospermidine synthase 2.5.1.44 0.654
5bsg NAPPyrroline-5-carboxylate reductase / 0.653
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.652
1e5q NDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming] 1.5.1.10 0.651
1p1h NADInositol-3-phosphate synthase 5.5.1.4 0.651
1i2b NADUDP-sulfoquinovose synthase, chloroplastic 3.13.1.1 0.650
1wwk NAD307aa long hypothetical phosphoglycerate dehydrogenase / 0.650
3f1k NAPUncharacterized oxidoreductase YciK 1 0.650
4hxy NDPPlm1 / 0.650