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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
5c3jUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
5c3jUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/1.000
5c3jUQ1Succinate dehydrogenase cytochrome b560/1.000
3vrbFTNSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.558
3vrbFTNCytochrome b-large subunit/0.558
3vr8RQXSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial/0.511
3vr8RQXCytochrome b-large subunit/0.511
3ae4N1MSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.445
3ae4N1MSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.445