Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l33F70Tankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4l33F70Tankyrase-22.4.2.301.000
4bu908CTankyrase-22.4.2.300.733
4bufF36Tankyrase-22.4.2.300.691
4l0s1UZTankyrase-22.4.2.300.672
4l321VFTankyrase-22.4.2.300.664
4avwG18Tankyrase-22.4.2.300.663
4buuF38Tankyrase-22.4.2.300.659
4l0i1UWTankyrase-22.4.2.300.655
4iueAJ4Tankyrase-22.4.2.300.649
4bueJQFTankyrase-22.4.2.300.632
4hlf15ZTankyrase-22.4.2.300.626
4l31F08Tankyrase-22.4.2.300.625
4l2k1V8Tankyrase-22.4.2.300.622
5aku29FTankyrase-22.4.2.300.621
4j22AJ7Tankyrase-22.4.2.300.620
4kzuA73Tankyrase-22.4.2.300.619
4l341VGTankyrase-22.4.2.300.619
4buxF35Tankyrase-22.4.2.300.614
4hkkAGITankyrase-22.4.2.300.612
4hkiFLNTankyrase-22.4.2.300.608
4l0t1V0Tankyrase-22.4.2.300.606
4bus32FTankyrase-22.4.2.300.605
4l2f1V3Tankyrase-22.4.2.300.603
4but31FTankyrase-22.4.2.300.600
4buiW2ETankyrase-22.4.2.300.598
3p0pNNFTankyrase-22.4.2.300.596
4hlm16STankyrase-22.4.2.300.596
4hlh20DTankyrase-22.4.2.300.595
4hknLU2Tankyrase-22.4.2.300.593
4bud29FTankyrase-22.4.2.300.585
4l0v1V1Tankyrase-22.4.2.300.579
3u9y09LTankyrase-22.4.2.300.576
4hl515WTankyrase-22.4.2.300.576
4j21AJ6Tankyrase-22.4.2.300.572
4l2g1V4Tankyrase-22.4.2.300.571
4bj9UHBTankyrase-22.4.2.300.552
4kzl20DTankyrase-22.4.2.300.552
4hmhF94Tankyrase-22.4.2.300.549
4buv16ITankyrase-22.4.2.300.546
4buwF33Tankyrase-22.4.2.300.540
4tkg09LTankyrase-22.4.2.300.531
4msk2C8Tankyrase-12.4.2.300.528
4bs4A64Tankyrase-22.4.2.300.503
4pnmNU1Tankyrase-22.4.2.300.499
4pnrG18Tankyrase-22.4.2.300.489
4bjbP34Tankyrase-22.4.2.300.470
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.468
3rsv3RSBeta-secretase 13.4.23.460.464
4k4eK4ETankyrase-12.4.2.300.463
4tjy3GNTankyrase-22.4.2.300.457
4i9i1DYTankyrase-12.4.2.300.456
2g8yNADHydroxycarboxylate dehydrogenase B/0.453
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.447
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.445
4l6s1WQPoly [ADP-ribose] polymerase 12.4.2.300.445
4j3mAJ8Tankyrase-22.4.2.300.444
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.442
4bfsZVSPantothenate kinase2.7.1.330.441
4l091URTankyrase-22.4.2.300.441
1xf0ASDAldo-keto reductase family 1 member C3/0.440