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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l2f1V3Tankyrase-22.4.2.30

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
4l2f1V3Tankyrase-22.4.2.301.000
4kzl20DTankyrase-22.4.2.300.817
4but31FTankyrase-22.4.2.300.777
4l0s1UZTankyrase-22.4.2.300.771
4l0v1V1Tankyrase-22.4.2.300.747
4buuF38Tankyrase-22.4.2.300.743
4bu908CTankyrase-22.4.2.300.739
4bufF36Tankyrase-22.4.2.300.717
4hlf15ZTankyrase-22.4.2.300.716
5aku29FTankyrase-22.4.2.300.691
4hlh20DTankyrase-22.4.2.300.653
4hlm16STankyrase-22.4.2.300.649
4bueJQFTankyrase-22.4.2.300.648
4buxF35Tankyrase-22.4.2.300.648
4l33F70Tankyrase-22.4.2.300.645
4avwG18Tankyrase-22.4.2.300.644
4iueAJ4Tankyrase-22.4.2.300.641
4l0i1UWTankyrase-22.4.2.300.641
4bus32FTankyrase-22.4.2.300.633
4hkkAGITankyrase-22.4.2.300.628
4l321VFTankyrase-22.4.2.300.628
4l2k1V8Tankyrase-22.4.2.300.627
4l341VGTankyrase-22.4.2.300.624
4l31F08Tankyrase-22.4.2.300.622
4l0t1V0Tankyrase-22.4.2.300.621
4hl515WTankyrase-22.4.2.300.619
4l2g1V4Tankyrase-22.4.2.300.617
4hmhF94Tankyrase-22.4.2.300.608
4hkiFLNTankyrase-22.4.2.300.603
4j21AJ6Tankyrase-22.4.2.300.602
3p0pNNFTankyrase-22.4.2.300.600
4l091URTankyrase-22.4.2.300.574
4buv16ITankyrase-22.4.2.300.572
4bj9UHBTankyrase-22.4.2.300.571
4pnrG18Tankyrase-22.4.2.300.558
4buwF33Tankyrase-22.4.2.300.546
4bs4A64Tankyrase-22.4.2.300.545
4msk2C8Tankyrase-12.4.2.300.530
4pnmNU1Tankyrase-22.4.2.300.519
4tkg09LTankyrase-22.4.2.300.519
4bjbP34Tankyrase-22.4.2.300.499
4k4eK4ETankyrase-12.4.2.300.486
4j3lAJ5Tankyrase-22.4.2.300.477
4avuLDRTankyrase-22.4.2.300.473
5eghPCEctonucleotide pyrophosphatase/phosphodiesterase family member 6/0.473
4tjy3GNTankyrase-22.4.2.300.453
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.452
2bf7HBIPteridine reductase 11.5.1.330.451
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.447
2dw4FADLysine-specific histone demethylase 1A10.447
4i9i1DYTankyrase-12.4.2.300.446
5dp2NAPCurF/0.446
2bfaCB3Pteridine reductase 11.5.1.330.445
3ldfSAHUncharacterized protein/0.440