scPDB - Distribution of Cavity Similarity values of 4j21 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4j21	AJ6	Tankyrase-2	2.4.2.30

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4j21	AJ6	Tankyrase-2	2.4.2.30	1.000
4hlf	15Z	Tankyrase-2	2.4.2.30	0.638
4iue	AJ4	Tankyrase-2	2.4.2.30	0.630
4l0i	1UW	Tankyrase-2	2.4.2.30	0.628
4bu9	08C	Tankyrase-2	2.4.2.30	0.602
4hlm	16S	Tankyrase-2	2.4.2.30	0.602
4hlh	20D	Tankyrase-2	2.4.2.30	0.598
4l0s	1UZ	Tankyrase-2	2.4.2.30	0.598
4l32	1VF	Tankyrase-2	2.4.2.30	0.598
4bue	JQF	Tankyrase-2	2.4.2.30	0.595
4j22	AJ7	Tankyrase-2	2.4.2.30	0.592
4hkk	AGI	Tankyrase-2	2.4.2.30	0.591
4l31	F08	Tankyrase-2	2.4.2.30	0.585
4bux	F35	Tankyrase-2	2.4.2.30	0.583
4l33	F70	Tankyrase-2	2.4.2.30	0.583
4avw	G18	Tankyrase-2	2.4.2.30	0.582
4buf	F36	Tankyrase-2	2.4.2.30	0.582
4l2f	1V3	Tankyrase-2	2.4.2.30	0.581
4l2k	1V8	Tankyrase-2	2.4.2.30	0.578
3u9y	09L	Tankyrase-2	2.4.2.30	0.575
4hl5	15W	Tankyrase-2	2.4.2.30	0.572
5aku	29F	Tankyrase-2	2.4.2.30	0.571
4kzl	20D	Tankyrase-2	2.4.2.30	0.567
4l2g	1V4	Tankyrase-2	2.4.2.30	0.567
4l0t	1V0	Tankyrase-2	2.4.2.30	0.557
4krs	1SX	Tankyrase-1	2.4.2.30	0.552
4l0v	1V1	Tankyrase-2	2.4.2.30	0.552
3p0p	NNF	Tankyrase-2	2.4.2.30	0.548
4tkg	09L	Tankyrase-2	2.4.2.30	0.548
4bus	32F	Tankyrase-2	2.4.2.30	0.546
4pnr	G18	Tankyrase-2	2.4.2.30	0.546
4but	31F	Tankyrase-2	2.4.2.30	0.544
4hki	FLN	Tankyrase-2	2.4.2.30	0.533
4bj9	UHB	Tankyrase-2	2.4.2.30	0.530
4hmh	F94	Tankyrase-2	2.4.2.30	0.528
4buw	F33	Tankyrase-2	2.4.2.30	0.525
4pnm	NU1	Tankyrase-2	2.4.2.30	0.514
4j3l	AJ5	Tankyrase-2	2.4.2.30	0.505
4tjy	3GN	Tankyrase-2	2.4.2.30	0.497
4bs4	A64	Tankyrase-2	2.4.2.30	0.495
4msk	2C8	Tankyrase-1	2.4.2.30	0.494
4l09	1UR	Tankyrase-2	2.4.2.30	0.487
4hyf	1AK	Tankyrase-2	2.4.2.30	0.476
4bjb	P34	Tankyrase-2	2.4.2.30	0.470
4avu	LDR	Tankyrase-2	2.4.2.30	0.455
1pax	DHQ	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.452
4k4e	K4E	Tankyrase-1	2.4.2.30	0.452
1knr	FAD	L-aspartate oxidase	1.4.3.16	0.447
4i9i	1DY	Tankyrase-1	2.4.2.30	0.445
3mau	PLR	Putative sphingosine-1-phosphate lyase	/	0.442
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.442
4li8	1XQ	Tankyrase-1	2.4.2.30	0.441