scPDB - Distribution of Cavity Similarity values of 4gh1 entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
4gh1	0WX	Queuine tRNA-ribosyltransferase	2.4.2.29	1.000
3sm0	AEK	Queuine tRNA-ribosyltransferase	2.4.2.29	0.787
4gg9	0WW	Queuine tRNA-ribosyltransferase	2.4.2.29	0.765
4gh3	0EV	Queuine tRNA-ribosyltransferase	2.4.2.29	0.711
3ge7	AFQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.673
4fps	0UX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.650
1q63	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.644
4gkt	0O1	Queuine tRNA-ribosyltransferase	2.4.2.29	0.631
1y5v	NE8	Queuine tRNA-ribosyltransferase	2.4.2.29	0.623
2z1x	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.616
1q4w	DQU	Queuine tRNA-ribosyltransferase	2.4.2.29	0.614
4gi4	0EX	Queuine tRNA-ribosyltransferase	2.4.2.29	0.605
1q65	BHB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.596
1y5x	E89	Queuine tRNA-ribosyltransferase	2.4.2.29	0.587
1f3e	DPZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.580
1efz	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.577
4giy	0WY	Queuine tRNA-ribosyltransferase	2.4.2.29	0.577
4fr1	0V2	Queuine tRNA-ribosyltransferase	2.4.2.29	0.573
1k4g	AIQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.571
2bbf	344	Queuine tRNA-ribosyltransferase	2.4.2.29	0.569
1y5w	NEZ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.565
2qzr	S79	Queuine tRNA-ribosyltransferase	2.4.2.29	0.562
1p0e	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.558
1ozq	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.551
1q66	KMB	Queuine tRNA-ribosyltransferase	2.4.2.29	0.546
2z1w	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.541
4hsh	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.540
4q8p	CKR	Queuine tRNA-ribosyltransferase	2.4.2.29	0.539
4hvx	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.535
4gcx	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.534
4hqv	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.530
1k4h	APQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.527
2pot	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.524
4h7z	GUN	Queuine tRNA-ribosyltransferase	2.4.2.29	0.524
3gc4	AAQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.522
4fsa	0V3	Queuine tRNA-ribosyltransferase	2.4.2.29	0.510
1pxg	PRF	Queuine tRNA-ribosyltransferase	2.4.2.29	0.505
1n2v	BDI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.503
3gc5	2MQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.498
3blo	QEI	Queuine tRNA-ribosyltransferase	2.4.2.29	0.489
3n87	N87	3-dehydroquinate dehydratase	4.2.1.10	0.480
3anm	NDP	1-deoxy-D-xylulose 5-phosphate reductoisomerase	1.1.1.267	0.468
1efy	BZC	Poly [ADP-ribose] polymerase 1	2.4.2.30	0.461
2oci	TYC	Valacyclovir hydrolase	3.1	0.460
3rsv	3RS	Beta-secretase 1	3.4.23.46	0.460
2g28	TDK	Pyruvate dehydrogenase E1 component	1.2.4.1	0.458
3sn6	P0G	Beta-2 adrenergic receptor	/	0.458
3fhx	PLP	Pyridoxal kinase	2.7.1.35	0.455
4s1h	ADP	Pyridoxal kinase, putative	/	0.455
1ve3	SAM	Uncharacterized protein	/	0.453
2ivp	ATP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.452
2io6	330	Wee1-like protein kinase	2.7.10.2	0.451
3biz	61E	Wee1-like protein kinase	2.7.10.2	0.451
4bgb	ADP	Predicted molecular chaperone distantly related to HSP70-fold metalloproteases	/	0.450
4da8	BG2	Purine nucleoside phosphorylase DeoD-type	2.4.2.1	0.449
1nbi	SAM	Glycine N-methyltransferase	2.1.1.20	0.448
3p9k	SAH	Caffeic acid O-methyltransferase	/	0.448
1it7	GUN	tRNA-guanine(15) transglycosylase	2.4.2.48	0.447
2gev	COK	Pantothenate kinase	2.7.1.33	0.445
2gjn	FMN	Nitronate monooxygenase	1.13.12.16	0.445
4b78	KGG	Beta-secretase 1	3.4.23.46	0.445
1t4c	COA	Formyl-CoA:oxalate CoA-transferase	/	0.444
1u0w	STL	Chalcone synthase 2	2.3.1.74	0.444
2yac	937	Serine/threonine-protein kinase PLK1	2.7.11.21	0.444
2dxi	ATP	Glutamate--tRNA ligase	6.1.1.17	0.443
2fb8	215	Serine/threonine-protein kinase B-raf	2.7.11.1	0.442
3bll	BPQ	Queuine tRNA-ribosyltransferase	2.4.2.29	0.442
1h6c	NDP	Glucose--fructose oxidoreductase	1.1.99.28	0.441
2gqf	FAD	Uncharacterized protein HI_0933	/	0.441
4af6	FAD	Ferredoxin--NADP reductase, leaf isozyme, chloroplastic	1.18.1.2	0.440
4b1e	6T6	Beta-secretase 1	3.4.23.46	0.440