sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 1.000 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.705 | |
| 4eu8 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.616 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.550 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.496 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.482 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.457 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.452 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.449 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.442 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.440 |