sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4b42 | 942 | Glucose-1-phosphate thymidylyltransferase | / | 1.000 | |
| 4b5b | BBE | Glucose-1-phosphate thymidylyltransferase | / | 0.751 | |
| 4b4g | KKT | Glucose-1-phosphate thymidylyltransferase | / | 0.692 | |
| 4b2w | BZ0 | Glucose-1-phosphate thymidylyltransferase | / | 0.662 | |
| 4asj | N6A | Glucose-1-phosphate thymidylyltransferase | / | 0.619 | |
| 4b4b | GJB | Glucose-1-phosphate thymidylyltransferase | / | 0.618 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.489 | |
| 4asy | N5Y | Glucose-1-phosphate thymidylyltransferase | / | 0.486 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.467 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.455 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.447 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.446 | |
| 1t2b | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.443 | |
| 2y3s | TIR | TamL | / | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.442 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4iax | LIZ | Neutrophil gelatinase-associated lipocalin | / | 0.440 |