Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.149

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3x065GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1491.000
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.667
3x025GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.634
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.617
3x0c5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.526
3x03ANPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.468