sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3o8g | O8G | HTH-type transcriptional regulator EthR |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 1.000 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.731 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.637 | |
| 3tp0 | FO5 | HTH-type transcriptional regulator EthR | / | 0.627 | |
| 3g1m | RF3 | HTH-type transcriptional regulator EthR | / | 0.623 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.617 | |
| 3sfi | 3SF | HTH-type transcriptional regulator EthR | / | 0.600 | |
| 3g1l | RF2 | HTH-type transcriptional regulator EthR | / | 0.598 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.550 | |
| 3g1o | RF1 | HTH-type transcriptional regulator EthR | / | 0.499 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.454 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.448 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 3gph | OID | Cytochrome P450 2E1 | 1.14.13 | 0.443 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.443 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.442 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.442 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.440 | |
| 1p91 | SAM | 23S rRNA (guanine(745)-N(1))-methyltransferase | / | 0.440 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3cz7 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.440 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.440 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.440 |