sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3nlc | FAD | Uncharacterized protein |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3nlc | FAD | Uncharacterized protein | / | 1.000 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.506 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.504 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.495 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.480 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.479 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.478 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.473 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.471 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.468 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.467 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.460 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.451 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.450 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.449 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.448 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.447 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.447 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.446 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.446 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.444 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.444 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.443 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.443 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.443 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.443 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.442 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.440 |