sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3moh	GDP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3moh	GDP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	1.000
1khb	GCP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.560
2qf2	GDP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.555
1m51	TSX	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.541
4r43	GDP	Phosphoenolpyruvate carboxykinase [GTP]	/	0.538
4wpu	GDP	Phosphoenolpyruvate carboxykinase [GTP]	/	0.515
5i67	GDP	Phosphoenolpyruvate carboxykinase [GTP]	/	0.494
1khe	GCP	Phosphoenolpyruvate carboxykinase, cytosolic [GTP]	4.1.1.32	0.489