Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3lqlLDTAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3lqlLDTAldose reductase1.1.1.211.000
3lboLDTAldose reductase1.1.1.210.871
3m4h388Aldose reductase1.1.1.210.811
3m64393Aldose reductase1.1.1.210.723
2fz9ZSTAldose reductase1.1.1.210.701
2dv0ZSTAldose reductase1.1.1.210.678
1z8962PAldose reductase1.1.1.210.677
2pdxZSTAldose reductase1.1.1.210.668
4yu153NAldose reductase1.1.1.210.657
1t40ID5Aldose reductase1.1.1.210.646
1z3n3NAAldose reductase1.1.1.210.646
2ikj393Aldose reductase1.1.1.210.642
1t41ID5Aldose reductase1.1.1.210.639
4gca2X9Aldose reductase1.1.1.210.639
2ikhLITAldose reductase1.1.1.210.636
2hv5ZSTAldose reductase1.1.1.210.634
2duxZSTAldose reductase1.1.1.210.629
2iki388Aldose reductase1.1.1.210.622
3lz5LDTAldose reductase1.1.1.210.616
3mb9ZSTAldose reductase1.1.1.210.616
2i16LDTAldose reductase1.1.1.210.612
2hvnZSTAldose reductase1.1.1.210.603
2fz8ZSTAldose reductase1.1.1.210.599
2qxwLDTAldose reductase1.1.1.210.597
2pdu393Aldose reductase1.1.1.210.589
3m0iZSTAldose reductase1.1.1.210.587
1pwlBFIAldose reductase1.1.1.210.583
2pdc393Aldose reductase1.1.1.210.576
3lenZSTAldose reductase1.1.1.210.576
3mc5393Aldose reductase1.1.1.210.576
2pdbZSTAldose reductase1.1.1.210.572
2pdg47DAldose reductase1.1.1.210.572
3ld5LDTAldose reductase1.1.1.210.571
3ghrLDTAldose reductase1.1.1.210.570
2pd5ZSTAldose reductase1.1.1.210.565
1us0LDTAldose reductase1.1.1.210.561
2pdn47DAldose reductase1.1.1.210.560
2i17LDTAldose reductase1.1.1.210.556
3ghuLDTAldose reductase1.1.1.210.555
2duzZSTAldose reductase1.1.1.210.554
1ieiZESAldose reductase1.1.1.210.553
1frbZSTAldose reductase-related protein 2/0.552
2fzdTOLAldose reductase1.1.1.210.552
2pdp393Aldose reductase1.1.1.210.551
2pdfZSTAldose reductase1.1.1.210.548
2pdh47DAldose reductase1.1.1.210.548
2pdq47DAldose reductase1.1.1.210.543
2pzn393Aldose reductase1.1.1.210.539
2hvoZSTAldose reductase1.1.1.210.537
3g5eQ74Aldose reductase1.1.1.210.537
3t423T4Aldose reductase1.1.1.210.537
3ghtLDTAldose reductase1.1.1.210.527
3ghsLDTAldose reductase1.1.1.210.518
2pdj393Aldose reductase1.1.1.210.514
1el3I84Aldose reductase1.1.1.210.495
1ah3TOLAldose reductase1.1.1.210.487
2pdlTOLAldose reductase1.1.1.210.479
2agtFIDAldose reductase1.1.1.210.478
5liu388Aldo-keto reductase family 1 member B101.1.10.476
2pdwFIDAldose reductase1.1.1.210.470
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.463
2f2kTGGAldose reductase1.1.1.210.458
2fzbTOLAldose reductase1.1.1.210.457
2pdkSBIAldose reductase1.1.1.210.457
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.455
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.455
2f3815MAldo-keto reductase family 1 member C3/0.454
1ekoI84Aldose reductase1.1.1.210.453
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2oazI96Methionine aminopeptidase 2/0.448
4jtrIZPAldo-keto reductase family 1 member C2/0.447
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.446
4dbw511Aldo-keto reductase family 1 member C3/0.445
1e66HUXAcetylcholinesterase3.1.1.70.443
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
2cbqTH2Neocarzinostatin/0.442
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
1odcA8BAcetylcholinesterase3.1.1.70.440
3v35NTIAldose reductase1.1.1.210.440