sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3l70 | JZV | Cytochrome b |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3l70 | JZV | Cytochrome b | / | 1.000 | |
| 3l71 | AZO | Cytochrome b | / | 0.604 | |
| 3tgu | WF3 | Cytochrome b | / | 0.585 | |
| 1sqb | AZO | Cytochrome b | / | 0.534 | |
| 1sqp | MYX | Cytochrome b | / | 0.520 | |
| 3h1j | SMA | Cytochrome b | / | 0.485 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.471 | |
| 3anl | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.462 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.462 | |
| 3t8x | T8X | T-cell surface glycoprotein CD1b | / | 0.458 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.451 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.449 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.449 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.449 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 2acw | UPG | Glycosyltransferase | / | 0.446 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.446 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.443 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.442 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 3bhl | THG | Thymidylate synthase | / | 0.441 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.440 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.440 |