Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.2

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3gwlFADFAD-linked sulfhydryl oxidase1.8.3.21.000
3tk0FADFAD-linked sulfhydryl oxidase ALR1.8.3.20.548
1oqcFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.547
3u2lFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.538
3r7cFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.524
3u5sFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.510
3mbgFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.508
3u2mFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.508
4e0hFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.499
4ldkFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.486
4e0iFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.485
4lb2DM5Serum albumin/0.483
2hj3FADFAD-linked sulfhydryl oxidase ERV1/0.479
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.478
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
1pd9CO4Dihydrofolate reductase1.5.1.30.466
2bxqIMNSerum albumin/0.464
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.461
1diuBDMDihydrofolate reductase1.5.1.30.458
3h3r14HCollagen type IV alpha-3-binding protein/0.458
1rp4FADEndoplasmic oxidoreductin-11.8.40.457
2wpwACOOrf14/0.457
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.456
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.456
1rq1FADEndoplasmic oxidoreductin-11.8.40.455
2bxmIMNSerum albumin/0.455
5bp9SAHPutative methyltransferase protein/0.455
2c27ACOMycothiol acetyltransferase2.3.1.1890.454
2ykiYKIHeat shock protein HSP 90-alpha/0.453
3eej53RUncharacterized protein/0.452
2g2hP16Tyrosine-protein kinase ABL12.7.10.20.451
4hw219HInduced myeloid leukemia cell differentiation protein Mcl-1/0.451
3kpkFADSulfide-quinone reductase/0.450
2znnS44Peroxisome proliferator-activated receptor alpha/0.449
4j6cSTRCytochrome P450 monooxygenase/0.449
4eftEFTHeat shock protein HSP 90-alpha/0.448
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
3s79ASDAromatase1.14.14.140.446
4em9TCEPeroxisome proliferator-activated receptor gamma/0.446
5hs1VORLanosterol 14-alpha demethylase/0.446
1q5dEPBEpothilone C/D epoxidase1.140.445
4eph0RKCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.445
6cp4CAMCamphor 5-monooxygenase1.14.15.10.445
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2ykeYKEHeat shock protein HSP 90-alpha/0.444
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.443
1pkfEPDEpothilone C/D epoxidase1.140.443
1uy8PU5Heat shock protein HSP 90-alpha/0.443
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.442
3oetNADErythronate-4-phosphate dehydrogenase/0.442
4bqpVMYEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.442
5ab6CAANonspecific lipid-transfer protein, putative/0.442
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.441
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
3h3sH15Collagen type IV alpha-3-binding protein/0.441
2lbaCHOFatty acid binding protein 6/0.440
2yee2ECHeat shock protein HSP 90-alpha/0.440