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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gl2D3MDdmC

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3gl2D3MDdmC/1.000
3gtsD3MDdmC/0.551
3gb4D3MDdmC/0.537
3gobHXXDdmC/0.465
3vrwYS5Vitamin D3 receptor/0.462
2givACOHistone acetyltransferase KAT8/0.454
1xkdNAPIsocitrate dehydrogenase [NADP]/0.451
4iah1DXAlr2278 protein/0.451
4iae1DXAlr2278 protein/0.450
2y0mACOHistone acetyltransferase KAT8/0.447
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.440
3l6jZ90Alr2278 protein/0.440
4jqh1MFAlr2278 protein/0.440