sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity	Align
3dk4	FAD	Glutathione reductase, mitochondrial	1.8.1.7	1.000
3dk8	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.881
3dk9	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.838
1bwc	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.622
1gra	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.610
1k4q	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.610
1gre	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.608
1grg	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.605
4gr1	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.600
3grs	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.599
1grh	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.598
1gsn	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.593
2gh5	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.520
2v6o	FAD	Thioredoxin glutathione reductase	/	0.512
1grb	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.507
3sqp	FAD	Glutathione reductase, mitochondrial	1.8.1.7	0.493
3dgz	FAD	Thioredoxin reductase 2, mitochondrial	1.8.1.9	0.486
2nvk	FAD	Thioredoxin reductase 1, mitochondrial	1.8.1.9	0.475
2rab	FAD	Glutathione amide reductase	/	0.447