sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yg3 | FAD | Putrescine oxidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2yg3 | FAD | Putrescine oxidase | / | 1.000 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.655 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.633 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.539 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.530 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.524 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.522 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.509 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.504 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.495 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.494 | |
| 3rha | FDA | Putrescine oxidase | / | 0.487 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.486 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.481 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.477 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.476 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.472 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.468 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.466 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.455 | |
| 1drf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.450 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.449 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.446 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.441 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.440 |