sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 1.000 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.650 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.644 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.641 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.641 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.638 | |
| 3wrh | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.633 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.632 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.630 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.629 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.628 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.626 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.626 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.625 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.624 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.623 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.622 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.622 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.620 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.617 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.616 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.615 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.613 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.609 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.607 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.605 | |
| 1yrd | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.604 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.603 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.602 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.599 | |
| 2a1m | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.594 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.593 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.593 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.593 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.592 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.591 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.588 | |
| 4l4f | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.588 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.587 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.582 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.577 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.576 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.576 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.572 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.569 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.557 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.553 | |
| 1rf9 | DBR | Camphor 5-monooxygenase | 1.14.15.1 | 0.552 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.548 | |
| 1jip | KTN | 6-deoxyerythronolide B hydroxylase | / | 0.547 | |
| 1re9 | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.544 | |
| 3p6o | ETG | Camphor 5-monooxygenase | 1.14.15.1 | 0.532 | |
| 3p6m | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.525 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.523 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.511 | |
| 5hs1 | VOR | Lanosterol 14-alpha demethylase | / | 0.508 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.489 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.482 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.481 | |
| 1eup | ASD | 6-deoxyerythronolide B hydroxylase | / | 0.474 | |
| 1q5d | EPB | Epothilone C/D epoxidase | 1.14 | 0.472 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.472 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.467 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.466 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.464 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.463 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.460 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.458 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.456 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.456 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.456 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.455 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.454 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.446 | |
| 4b7s | QLE | Cytochrome P450 monooxygenase PikC | / | 0.446 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.444 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.443 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.440 |