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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2qaeFADDihydrolipoyl dehydrogenase1.8.1.4

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2qaeFADDihydrolipoyl dehydrogenase1.8.1.41.000
2f5zFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.585
3ladFADDihydrolipoyl dehydrogenase/0.584
2yquFADDihydrolipoyl dehydrogenase/0.567
2eq9FADDihydrolipoyl dehydrogenase/0.561
3rnmFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.556
1jehFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.536
1lpfFADDihydrolipoyl dehydrogenase1.8.1.40.532
1zy8FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.521
4jq9FADDihydrolipoyl dehydrogenase/0.520
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.501
2eq6FADDihydrolipoyl dehydrogenase/0.494
3urhFADDihydrolipoyl dehydrogenase/0.494
1zx9FADMercuric reductase1.16.1.10.479
1zk7FADMercuric reductase1.16.1.10.477
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.467
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.463
3cgcFADCoenzyme A disulfide reductase/0.451
3cgbFADCoenzyme A disulfide reductase/0.450