sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2pwy | SAH | tRNA (adenine(58)-N(1))-methyltransferase TrmI | 2.1.1.220 | 1.000 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.482 | |
| 1eg2 | MTA | Modification methylase RsrI | 2.1.1.72 | 0.474 | |
| 2yvl | SAM | tRNA (adenine(58)-N(1))-methyltransferase TrmI | / | 0.466 | |
| 2plw | SAM | Ribosomal RNA methyltransferase, putative | / | 0.461 | |
| 3uj7 | SAM | Phosphoethanolamine N-methyltransferase | / | 0.456 | |
| 2r0u | M54 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.452 | |
| 3tlj | SAH | Uncharacterized protein | / | 0.450 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4iv0 | SAM | Phosphoethanolamine N-methyltransferase, putative | / | 0.447 | |
| 3ua3 | SAH | Protein arginine N-methyltransferase 5 | / | 0.443 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.441 | |
| 3b89 | 5GP | 16S rRNA methylase | / | 0.441 | |
| 1nw5 | SAM | Modification methylase RsrI | 2.1.1.72 | 0.440 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 |