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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2pdg47DAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2pdg47DAldose reductase1.1.1.211.000
2hvoZSTAldose reductase1.1.1.210.571
2pdxZSTAldose reductase1.1.1.210.560
2fz8ZSTAldose reductase1.1.1.210.553
2pdmZSTAldose reductase1.1.1.210.553
2duxZSTAldose reductase1.1.1.210.548
3mb9ZSTAldose reductase1.1.1.210.539
2pdiZSTAldose reductase1.1.1.210.538
2pdu393Aldose reductase1.1.1.210.534
3ld5LDTAldose reductase1.1.1.210.523
2pdh47DAldose reductase1.1.1.210.521
2hvnZSTAldose reductase1.1.1.210.520
2fz9ZSTAldose reductase1.1.1.210.515
2pdfZSTAldose reductase1.1.1.210.515
2duzZSTAldose reductase1.1.1.210.513
4yu153NAldose reductase1.1.1.210.512
4gca2X9Aldose reductase1.1.1.210.505
2i17LDTAldose reductase1.1.1.210.503
1z8962PAldose reductase1.1.1.210.501
3ghtLDTAldose reductase1.1.1.210.496
2hv5ZSTAldose reductase1.1.1.210.488
3g5eQ74Aldose reductase1.1.1.210.487
3m4h388Aldose reductase1.1.1.210.486
1ieiZESAldose reductase1.1.1.210.485
2dv0ZSTAldose reductase1.1.1.210.483
2iqdLPAAldose reductase1.1.1.210.483
2qxwLDTAldose reductase1.1.1.210.482
3ghsLDTAldose reductase1.1.1.210.482
2pd5ZSTAldose reductase1.1.1.210.481
1t41ID5Aldose reductase1.1.1.210.478
3lboLDTAldose reductase1.1.1.210.478
3m64393Aldose reductase1.1.1.210.477
2pdbZSTAldose reductase1.1.1.210.470
1t40ID5Aldose reductase1.1.1.210.469
2pdn47DAldose reductase1.1.1.210.468
3ghrLDTAldose reductase1.1.1.210.467
1zuaTOLAldo-keto reductase family 1 member B101.1.10.465
2pdj393Aldose reductase1.1.1.210.465
1z3n3NAAldose reductase1.1.1.210.464
1pwlBFIAldose reductase1.1.1.210.462
2ikj393Aldose reductase1.1.1.210.462
3lenZSTAldose reductase1.1.1.210.462
3u2cSUZAldose reductase1.1.1.210.462
3lqlLDTAldose reductase1.1.1.210.461
2pzn393Aldose reductase1.1.1.210.459
3ghuLDTAldose reductase1.1.1.210.459
3lz5LDTAldose reductase1.1.1.210.457
3t423T4Aldose reductase1.1.1.210.457
3m0iZSTAldose reductase1.1.1.210.454
3s3gTLTAldose reductase1.1.1.210.454
2iki388Aldose reductase1.1.1.210.453
2inzOHPAldose reductase1.1.1.210.453
2f2kTGGAldose reductase1.1.1.210.450
2pdkSBIAldose reductase1.1.1.210.448
1frbZSTAldose reductase-related protein 2/0.446
2pdc393Aldose reductase1.1.1.210.446