scPDB - Distribution of Cavity Similarity values of 2pdf entry / Site 1

Distribution of Cavity similarities measured by Shaper

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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :

PDB ID	HET	Uniprot Name	EC Number
2pdf	ZST	Aldose reductase	1.1.1.21

Complex with similar cavities

PDB ID	HET	Uniprot Name	EC Number	Cavity Similarity
2pdf	ZST	Aldose reductase	1.1.1.21	1.000
2pdh	47D	Aldose reductase	1.1.1.21	0.620
2pdu	393	Aldose reductase	1.1.1.21	0.606
2pdl	TOL	Aldose reductase	1.1.1.21	0.551
2pdj	393	Aldose reductase	1.1.1.21	0.548
2pdm	ZST	Aldose reductase	1.1.1.21	0.529
2fz8	ZST	Aldose reductase	1.1.1.21	0.524
2hvo	ZST	Aldose reductase	1.1.1.21	0.523
2pdi	ZST	Aldose reductase	1.1.1.21	0.517
2hvn	ZST	Aldose reductase	1.1.1.21	0.507
2dv0	ZST	Aldose reductase	1.1.1.21	0.496
2pdq	47D	Aldose reductase	1.1.1.21	0.495
1t40	ID5	Aldose reductase	1.1.1.21	0.494
2fzd	TOL	Aldose reductase	1.1.1.21	0.493
2pdg	47D	Aldose reductase	1.1.1.21	0.491
4gca	2X9	Aldose reductase	1.1.1.21	0.487
1zua	TOL	Aldo-keto reductase family 1 member B10	1.1.1	0.485
2hv5	ZST	Aldose reductase	1.1.1.21	0.485
2pdn	47D	Aldose reductase	1.1.1.21	0.485
3p2v	DOY	Aldose reductase	1.1.1.21	0.482
2iqd	LPA	Aldose reductase	1.1.1.21	0.481
2iki	388	Aldose reductase	1.1.1.21	0.479
1ah3	TOL	Aldose reductase	1.1.1.21	0.477
1z89	62P	Aldose reductase	1.1.1.21	0.477
2ikj	393	Aldose reductase	1.1.1.21	0.476
3t42	3T4	Aldose reductase	1.1.1.21	0.473
1z3n	3NA	Aldose reductase	1.1.1.21	0.472
2fzb	TOL	Aldose reductase	1.1.1.21	0.472
2duz	ZST	Aldose reductase	1.1.1.21	0.471
2pdx	ZST	Aldose reductase	1.1.1.21	0.470
3mc5	393	Aldose reductase	1.1.1.21	0.470
1t41	ID5	Aldose reductase	1.1.1.21	0.469
2pzn	393	Aldose reductase	1.1.1.21	0.468
3ghu	LDT	Aldose reductase	1.1.1.21	0.468
3m64	393	Aldose reductase	1.1.1.21	0.468
2fz9	ZST	Aldose reductase	1.1.1.21	0.467
3ght	LDT	Aldose reductase	1.1.1.21	0.467
2i17	LDT	Aldose reductase	1.1.1.21	0.461
3g5e	Q74	Aldose reductase	1.1.1.21	0.459
2i16	LDT	Aldose reductase	1.1.1.21	0.457
3ld5	LDT	Aldose reductase	1.1.1.21	0.457
3m4h	388	Aldose reductase	1.1.1.21	0.457
3ghs	LDT	Aldose reductase	1.1.1.21	0.456
3ghr	LDT	Aldose reductase	1.1.1.21	0.455
3w5e	NVW	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.455
2dux	ZST	Aldose reductase	1.1.1.21	0.453
3lbo	LDT	Aldose reductase	1.1.1.21	0.453
4dbw	511	Aldo-keto reductase family 1 member C3	/	0.453
1us0	LDT	Aldose reductase	1.1.1.21	0.452
2pdp	393	Aldose reductase	1.1.1.21	0.451
2qxw	LDT	Aldose reductase	1.1.1.21	0.450
3m0i	ZST	Aldose reductase	1.1.1.21	0.448
3lz5	LDT	Aldose reductase	1.1.1.21	0.447
2pd5	ZST	Aldose reductase	1.1.1.21	0.445
2pd9	FID	Aldose reductase	1.1.1.21	0.445
1xor	ZAR	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.444
1y60	H4M	5,6,7,8-tetrahydromethanopterin hydro-lyase	4.2.1.147	0.444
2f2k	TGG	Aldose reductase	1.1.1.21	0.444
1eko	I84	Aldose reductase	1.1.1.21	0.443
2nvc	ITA	Aldose reductase	1.1.1.21	0.443
2pdk	SBI	Aldose reductase	1.1.1.21	0.443
2pdc	393	Aldose reductase	1.1.1.21	0.442
3k4s	0MO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.442
4fam	0SZ	Aldo-keto reductase family 1 member C3	/	0.442
4yu1	53N	Aldose reductase	1.1.1.21	0.442
1pwl	BFI	Aldose reductase	1.1.1.21	0.441
2agt	FID	Aldose reductase	1.1.1.21	0.441
5liu	388	Aldo-keto reductase family 1 member B10	1.1.1	0.440