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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
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Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2fz8ZSTAldose reductase1.1.1.21

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2fz8ZSTAldose reductase1.1.1.211.000
2pdmZSTAldose reductase1.1.1.210.663
2pdiZSTAldose reductase1.1.1.210.595
2hv5ZSTAldose reductase1.1.1.210.574
2fz9ZSTAldose reductase1.1.1.210.568
2iqdLPAAldose reductase1.1.1.210.556
2iki388Aldose reductase1.1.1.210.546
2i16LDTAldose reductase1.1.1.210.541
1z8962PAldose reductase1.1.1.210.537
2hvoZSTAldose reductase1.1.1.210.533
2pdu393Aldose reductase1.1.1.210.532
2dv0ZSTAldose reductase1.1.1.210.530
2inzOHPAldose reductase1.1.1.210.527
2pdxZSTAldose reductase1.1.1.210.526
3ghrLDTAldose reductase1.1.1.210.525
2pdyFIDAldose reductase1.1.1.210.523
1ieiZESAldose reductase1.1.1.210.513
2pdg47DAldose reductase1.1.1.210.513
3mb9ZSTAldose reductase1.1.1.210.512
2hvnZSTAldose reductase1.1.1.210.505
3ghsLDTAldose reductase1.1.1.210.502
1z3n3NAAldose reductase1.1.1.210.492
2ikj393Aldose reductase1.1.1.210.491
3ghtLDTAldose reductase1.1.1.210.486
2pdlTOLAldose reductase1.1.1.210.485
2pdfZSTAldose reductase1.1.1.210.481
1t40ID5Aldose reductase1.1.1.210.477
2ikhLITAldose reductase1.1.1.210.477
2duzZSTAldose reductase1.1.1.210.474
2qxwLDTAldose reductase1.1.1.210.471
2pdh47DAldose reductase1.1.1.210.468
3g5eQ74Aldose reductase1.1.1.210.463
4gca2X9Aldose reductase1.1.1.210.462
3ghuLDTAldose reductase1.1.1.210.459
3m64393Aldose reductase1.1.1.210.458
2f2kTGGAldose reductase1.1.1.210.456
3lqlLDTAldose reductase1.1.1.210.455
2pdp393Aldose reductase1.1.1.210.452
1t41ID5Aldose reductase1.1.1.210.451
2pdwFIDAldose reductase1.1.1.210.449
2pzn393Aldose reductase1.1.1.210.448
2i17LDTAldose reductase1.1.1.210.446
2pdbZSTAldose reductase1.1.1.210.445
3ld5LDTAldose reductase1.1.1.210.443
2pd5ZSTAldose reductase1.1.1.210.442