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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.11

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.111.000
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.656
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.624
2f7z6EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.606
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.595
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.592
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.591
2uw5GVNcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.579
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.567
2vo6M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.566
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.543
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.526
2vo0M03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
3ow3SMYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.524
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.521
1ydrIQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.517
2uw0GVKcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.512
1q8uH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2gu8796cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.510
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.497
1q8tY27cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
3e8cG96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.487
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
3dndLL2cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
1sveI01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
3zo1SIJcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.484
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.483
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.479
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
2vnwM01cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
2vo3M04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
1svgI04cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2uw4L15cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3zo4QWIcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
4iacACPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
1xhaR68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
3aglA03cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4yxsEMUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443